预防结直肠癌癌症的最佳体力活动类型和剂量是多少?

IF 3.2 3区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Best Practice & Research Clinical Gastroenterology Pub Date : 2023-10-01 DOI:10.1016/j.bpg.2023.101841
Samuel T. Orange
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引用次数: 1

摘要

流行病学证据表明,较高水平的体育活动可将患癌症的相对风险降低20%。为了设计用于初级预防的最佳体育活动干预措施,重要的是了解体育活动的具体特征(类型、强度、总容量)如何影响结肠癌癌症风险降低的程度。提高我们对潜在生物学机制的理解,也将有助于操纵身体活动特征,以精确定位作用机制,并确定最有可能受益的人群。这篇综述综合了现有的最佳证据,以探索体育活动的类型和剂量如何调节体育活动对结肠癌的保护作用。
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What is the optimal type and dose of physical activity for colorectal cancer prevention?

Epidemiological evidence shows that higher levels of physical activity reduce the relative risk of colon cancer by up to 20%. To design optimal physical activity interventions for primary prevention, it is important to understand how the specific characteristics of physical activity (type, intensity, overall volume) influence the magnitude of colon cancer risk reduction. Improving our understanding of the underlying biological mechanisms will also help to manipulate physical activity characteristics to precisely target mechanisms of action and identify populations most likely to benefit. This review synthesizes the best available evidence to explore how the type and dose of physical activity moderate the protective effect of physical activity on colon cancer.

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来源期刊
CiteScore
5.50
自引率
0.00%
发文量
23
审稿时长
69 days
期刊介绍: Each topic-based issue of Best Practice & Research Clinical Gastroenterology will provide a comprehensive review of current clinical practice and thinking within the specialty of gastroenterology.
期刊最新文献
The role of the microbiome in immune checkpoint inhibitor colitis and hepatitis The role of the gut microbiome in regulating the response to immune checkpoint inhibitor therapy Gut microbiota in colorectal cancer: From pathogenesis to clinic Editorial Board Table of Contents
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