Weirong Bai , Tuanjie Wang , Xiaoming Yang , Zhenzhong Wang , Haibo Li , Jianliang Geng
{"title":"从益智果中分离得到两个新的倍半萜类化合物。","authors":"Weirong Bai , Tuanjie Wang , Xiaoming Yang , Zhenzhong Wang , Haibo Li , Jianliang Geng","doi":"10.1080/14786419.2023.2272282","DOIUrl":null,"url":null,"abstract":"<div><div>Two undescribed sesquiterpenoids, including one nor-eudesmane type (<strong>1</strong>) and one guaiane type (<strong>2</strong>), together with two known analogues (<strong>3</strong>-<strong>4</strong>) have been isolated and identified from the fruits of <em>Alpinia oxyphylla</em>. The structures of these new compounds were elucidated by extensive spectroscopic analyses (1D-, 2D-NMR, HRESIMS, IR, UV) and NMR calculations with DP4+ analysis. The anti-inflammatory activities of all isolates were evaluated by measuring their inhibitory effects on PGE<sub>2</sub> production in LPS stimulated RAW 264.7 macrophages.</div></div>","PeriodicalId":18990,"journal":{"name":"Natural Product Research","volume":"39 3","pages":"Pages 468-474"},"PeriodicalIF":1.9000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Two new sesquiterpenoids from the fruits of Alpinia oxyphylla\",\"authors\":\"Weirong Bai , Tuanjie Wang , Xiaoming Yang , Zhenzhong Wang , Haibo Li , Jianliang Geng\",\"doi\":\"10.1080/14786419.2023.2272282\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Two undescribed sesquiterpenoids, including one nor-eudesmane type (<strong>1</strong>) and one guaiane type (<strong>2</strong>), together with two known analogues (<strong>3</strong>-<strong>4</strong>) have been isolated and identified from the fruits of <em>Alpinia oxyphylla</em>. The structures of these new compounds were elucidated by extensive spectroscopic analyses (1D-, 2D-NMR, HRESIMS, IR, UV) and NMR calculations with DP4+ analysis. The anti-inflammatory activities of all isolates were evaluated by measuring their inhibitory effects on PGE<sub>2</sub> production in LPS stimulated RAW 264.7 macrophages.</div></div>\",\"PeriodicalId\":18990,\"journal\":{\"name\":\"Natural Product Research\",\"volume\":\"39 3\",\"pages\":\"Pages 468-474\"},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2025-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Natural Product Research\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://www.sciencedirect.com/org/science/article/pii/S1478641923022234\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, APPLIED\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Natural Product Research","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/org/science/article/pii/S1478641923022234","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
Two new sesquiterpenoids from the fruits of Alpinia oxyphylla
Two undescribed sesquiterpenoids, including one nor-eudesmane type (1) and one guaiane type (2), together with two known analogues (3-4) have been isolated and identified from the fruits of Alpinia oxyphylla. The structures of these new compounds were elucidated by extensive spectroscopic analyses (1D-, 2D-NMR, HRESIMS, IR, UV) and NMR calculations with DP4+ analysis. The anti-inflammatory activities of all isolates were evaluated by measuring their inhibitory effects on PGE2 production in LPS stimulated RAW 264.7 macrophages.
期刊介绍：
The aim of Natural Product Research is to publish important contributions in the field of natural product chemistry. The journal covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds.
The communications include coverage of work on natural substances of land and sea and of plants, microbes and animals. Discussions of structure elucidation, synthesis and experimental biosynthesis of natural products as well as developments of methods in these areas are welcomed in the journal. Finally, research papers in fields on the chemistry-biology boundary, eg. fermentation chemistry, plant tissue culture investigations etc., are accepted into the journal.
Natural Product Research issues will be subtitled either ""Part A - Synthesis and Structure"" or ""Part B - Bioactive Natural Products"". for details on this , see the forthcoming articles section.
All manuscript submissions are subject to initial appraisal by the Editor, and, if found suitable for further consideration, to peer review by independent, anonymous expert referees. All peer review is single blind and submission is online via ScholarOne Manuscripts.
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