高肠皮瘘患者的早期口服水合作用。

Neuro endocrinology letters Pub Date : 2023-10-23
Miloslav Mišánik, Marek Smolár, Martin Grajciar, Kristína Cmarková, Beata Drobná Sániová, Juraj Miklušica
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引用次数: 0

摘要

引言:肠皮瘘是指胃肠道和皮肤之间的异常连接。除了败血症的早期识别和治疗外,营养支持、伤口管理、用适当设置和及时的补液治疗充分补充流失的液体,以及控制瘘管的产生,都是治疗管理的第一步。材料和方法:作者概述了口服补液治疗,描述了个别溶液对瘘管的性质和效果。通过一组钠依赖性葡萄糖协同转运蛋白(钠-葡萄糖连接转运蛋白,SGLT1)将液体和电解质吸收到胃肠道中。讨论:文章中描述的水和电解质吸收机制可用于治疗高瘘患者。低渗液(水、茶)的用量不应超过500毫升/天。剩余的容量,取决于瘘管的损失,必须补充等渗液。通过对口服补液溶液的良好耐受性和对其他治疗步骤的依从性,可以在整个治疗期间保持口服摄入,而无需完全禁止,从而提高患者的整体舒适度。结论:减少低渗液(自来水、茶)的摄入和使用等渗溶液有助于减少瘘管的产生,从而有助于瘘管的自发闭合。
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Early oral hydration in patients with high enterocutaneous fistula.

Introduction: Enterocutaneous fistula is defined as an abnormal connection between the gastrointestinal tract and the skin. In addition to the early recognition and treatment of sepsis, nutritional support, wound management, the adequate replacement of lost fluids with a properly set and timely rehydration treatment, together with the control of fistula production represent the first steps in treatment management.

Material and methods: The authors present an overview of oral rehydration therapy, describing the properties and effects of individual solutions on fistula. The absorption of fluids and electrolytes into the gastrointestinal tract is performed by the group of sodium-dependent glucose cotransporters (sodium-glucose linked transporter, SGLT1).

Discussion: The water and electrolyte absorption mechanisms described in the article can be used in the treatment of a patient with a high fistula. The amount of administered hypotonic fluids (water, tea) should not exceed 500 ml/day. The remaining volume, depending on fistula loss, must be supplemented with isoosmolar fluids. With a good tolerance of oral rehydration solutions and compliance with the other steps of treatment, it is possible to remain on oral intake during the entire duration of treatment without the need to prohibit it completely, thus improving the patient's overall comfort.

Conclusion: Reducing the intake of hypotonic fluids (tap water, tea) and administering an isotonic solution help to reduce the production of the fistula, thereby contributing to its spontaneous closure.

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