循环性死亡后的肾脏捐赠:意大利威尼托地区的经验

Q4 Medicine Transplantation Reports Pub Date : 2023-01-01 DOI:10.1016/j.tpr.2023.100129
C. Di Bella , G. Feltrin , C. Silvestre , F. Tuci , M. Di Bello , E. Rosso , P. Rigotti , L. Furian
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引用次数: 1

摘要

循环系统死亡后捐献(DCD)是增加全球器官供应的一种很有前途的策略。鉴于捐赠者死亡申报需要20分钟的无接触期,意大利目前的立法框架是实施此类计划的主要障碍。在这项研究中,我们描述了自2017年开始应用DCD以来,威尼托的DCD报告活动、DCD捐赠者的采购和肾移植数量。我们考虑了捐赠者的特征(DCD马斯特里赫特分类、年龄、性别)以及每个捐赠者取回和移植的肾移植物数量。根据Karpinski-Remuzzi评分,对所有获得的肾移植物进行了原位低温灌注和植入前肾活检。监测灌注参数以预测移植后的功能恢复,组织学评估侧重于评估缺血性损伤的范围。根据威尼托的经验,组织学数据和低温灌注已被证明是决定肾脏是否适合移植的非常有用的工具。考虑到与意大利DCD捐赠计划相关的后勤、临床、伦理和技术问题,威尼托必须投入大量资源,以建立足够的技术专业知识并开发专门的护理途径。威尼托地区移植协调会鼓励并支持DCD活动的发展,增加了DCD捐赠者的肾移植。
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Kidney Donation after circulatory death: The Veneto Region experience in Italy
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来源期刊
Transplantation Reports
Transplantation Reports Medicine-Transplantation
CiteScore
0.60
自引率
0.00%
发文量
24
审稿时长
101 days
期刊介绍: To provide to national and regional audiences experiences unique to them or confirming of broader concepts originating in large controlled trials. All aspects of organ, tissue and cell transplantation clinically and experimentally. Transplantation Reports will provide in-depth representation of emerging preclinical, impactful and clinical experiences. -Original basic or clinical science articles that represent initial limited experiences as preliminary reports. -Clinical trials of therapies previously well documented in large trials but now tested in limited, special, ethnic or clinically unique patient populations. -Case studies that confirm prior reports but have occurred in patients displaying unique clinical characteristics such as ethnicities or rarely associated co-morbidities. Transplantation Reports offers these benefits: -Fast and fair peer review -Rapid, article-based publication -Unrivalled visibility and exposure for your research -Immediate, free and permanent access to your paper on Science Direct -Immediately citable using the article DOI
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