{"title":"伏立康唑对金毛犬腹腔内由顶精子梭孢菌引起的多发真菌性肉芽肿的有效治疗","authors":"Aritada Yoshimura , Ryuji Fukushima , Masaki Michishita , Miki Omura , Koichi Makimura , Daigo Azakami","doi":"10.1016/j.mmcr.2023.100611","DOIUrl":null,"url":null,"abstract":"<div><p><em>Scedosporium apiospermum</em> is a saprophytic filamentous fungus that is pathogenic to dogs. This report describes a case of <em>S. apiospermum</em> infection that caused multiple large peritoneal fungal granulomas in a dog with a history of jejunojejunostomy. The lesions were firmly attached to multiple organs and could not be surgically removed. In such cases, no precedent for the response to the treatment of this disease exists, and all affected dogs have died. This is the first report of an effective medical treatment for multiple intra-abdominal fungal granulomas using voriconazole.</p></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"42 ","pages":"Article 100611"},"PeriodicalIF":1.6000,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Multiple intra-abdominal fungal granulomas caused by Scedosporium apiospermum effectively treated with voriconazole in a Golden Retriever\",\"authors\":\"Aritada Yoshimura , Ryuji Fukushima , Masaki Michishita , Miki Omura , Koichi Makimura , Daigo Azakami\",\"doi\":\"10.1016/j.mmcr.2023.100611\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p><em>Scedosporium apiospermum</em> is a saprophytic filamentous fungus that is pathogenic to dogs. This report describes a case of <em>S. apiospermum</em> infection that caused multiple large peritoneal fungal granulomas in a dog with a history of jejunojejunostomy. The lesions were firmly attached to multiple organs and could not be surgically removed. In such cases, no precedent for the response to the treatment of this disease exists, and all affected dogs have died. This is the first report of an effective medical treatment for multiple intra-abdominal fungal granulomas using voriconazole.</p></div>\",\"PeriodicalId\":51724,\"journal\":{\"name\":\"Medical Mycology Case Reports\",\"volume\":\"42 \",\"pages\":\"Article 100611\"},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2023-09-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medical Mycology Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S221175392300043X\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, RESEARCH & EXPERIMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Mycology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S221175392300043X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
Multiple intra-abdominal fungal granulomas caused by Scedosporium apiospermum effectively treated with voriconazole in a Golden Retriever
Scedosporium apiospermum is a saprophytic filamentous fungus that is pathogenic to dogs. This report describes a case of S. apiospermum infection that caused multiple large peritoneal fungal granulomas in a dog with a history of jejunojejunostomy. The lesions were firmly attached to multiple organs and could not be surgically removed. In such cases, no precedent for the response to the treatment of this disease exists, and all affected dogs have died. This is the first report of an effective medical treatment for multiple intra-abdominal fungal granulomas using voriconazole.