The exposome approach to study children's health

The exposome represents an interdisciplinary science and promising field of research that can identify how multiple facets of the environment influences health across the lifespan. A particular sensitive and critical window for environmental exposures and exposure-associated health is during early life, especially childhood. Previous studies of the exposome during childhood are highlighted, including the external and internal exposome. Challenges, and potential ways to overcome them, of the childhood exposome are presented with the aims to improve exposome studies during early life.