自身抗体检测在慢性肝病中的应用

iLABMED Pub Date : 2023-06-14 DOI:10.1002/ila2.18
Jinyu Han, Jin Chen, Yajie Wang
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引用次数: 0

摘要

自身抗体(AAb)检测已成为自身免疫性肝病(AILD)的诊断标准之一,一些AAb已成为AILD的特异性生物标志物。此外,AAbs可以在非AILD患者中检测到,如病毒性肝炎和酒精性肝病。然而,AAbs在非AILD患者中的分布特征和致病机制尚不清楚。本文总结了几种常见临床慢性肝病(CLD)中AAb的特征,并讨论了AAb分析在CLD中的价值。
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Application of autoantibody detection in chronic liver disease

Autoantibody (AAb) detection has become one of the standards of diagnosis for autoimmune liver disease (AILD), and some AAbs have become specific biomarkers of AILD. In addition, AAbs can be detected in patients with non-AILDs, such as viral hepatitis and alcoholic liver disease. However, the distribution characteristics and pathogenic mechanisms of AAbs in patients with non-AILD are unclear. This article summarizes the characteristics of AAbs in several common clinical chronic liver diseases (CLDs) and discusses the value of AAb analysis in CLD.

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