多层脂质小管在过量水中的稳定性。

IF 2.2 4区 生物学 Q3 BIOPHYSICS European Biophysics Journal Pub Date : 2023-10-26 DOI:10.1007/s00249-023-01686-5
Tripta Bhatia
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引用次数: 0

摘要

在含有过量水的脂质溶致性阶段,多层小管(MLT)从缺陷中生长。建立了MLT稳定性的现象学模型,该模型是普遍的,独立于MLT的潜在增长机制。MLT的稳定性意味着它们处于流体静力平衡,并且作为具有压缩和弯曲弹性的弹性物体是稳定的。结果表明,即使在0.1atm的溶剂压差下,密度分布也没有显著改变,因此表明稳定性是由于捕获的溶剂。该结果对于层状稳定性模型具有足够的价值,并且可能具有超出所述MLT模型的含义,特别是在膜系统的其他模型中。
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Stability of multilamellar lipid tubules in excess water

In the lyotropic phase of lipids with excess water, multilamellar tubules (MLTs) grow from defects. A phenomenological model for the stability of MLTs is developed that is universal and independent of the underlying growth mechanisms of MLTs. The stability of MLTs implies that they are in hydrostatic equilibrium and stable as elastic objects that have compression and bending elasticity. The results show that even with solvent pressure differences of 0.1 atm, the density profile is not significantly altered, so suggesting the stability is due to the trapped solvent. The results are of sufficient value in relation to lamellar stability models and may have implications beyond the described MLT models, especially in other models of membrane systems.

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来源期刊
European Biophysics Journal
European Biophysics Journal 生物-生物物理
CiteScore
4.30
自引率
0.00%
发文量
43
审稿时长
6-12 weeks
期刊介绍: The journal publishes papers in the field of biophysics, which is defined as the study of biological phenomena by using physical methods and concepts. Original papers, reviews and Biophysics letters are published. The primary goal of this journal is to advance the understanding of biological structure and function by application of the principles of physical science, and by presenting the work in a biophysical context. Papers employing a distinctively biophysical approach at all levels of biological organisation will be considered, as will both experimental and theoretical studies. The criteria for acceptance are scientific content, originality and relevance to biological systems of current interest and importance. Principal areas of interest include: - Structure and dynamics of biological macromolecules - Membrane biophysics and ion channels - Cell biophysics and organisation - Macromolecular assemblies - Biophysical methods and instrumentation - Advanced microscopics - System dynamics.
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