SARS-CoV-2受体及其在细胞感染中的作用

P. P. Avdonin, E. Yu. Rybakova, S. K. Trufanov, P. V. Avdonin
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引用次数: 1

摘要

由SARS-CoV-2引起的新型冠状病毒感染(COVID-19)大流行已多次超过SARS-CoV和MERS-CoV引起的流行。其原因是SARS-CoV-2蛋白序列中存在与宿主细胞表面更广泛的受体蛋白相互作用的位点。在这篇综述中,我们考虑了SARS-CoV和SARS-CoV-2共有的已知受体和SARS-CoV-2特异性的新受体。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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SARS-CoV-2 Receptors and Their Involvement in Cell Infection

The new coronavirus infection (COVID-19) pandemic caused by SARS-CoV-2 has many times surpassed the epidemics caused by SARS-CoV and MERS-CoV. The reason for this was the presence of sites in the protein sequence of SARS-CoV-2 that provide interaction with a broader range of receptor proteins on the host cell surface. In this review, we consider both already known receptors common to SARS-CoV and SARS-CoV-2 and new receptors specific to SARS-CoV-2.

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来源期刊
CiteScore
1.40
自引率
0.00%
发文量
28
期刊介绍: Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology   is an international peer reviewed journal that publishes original articles on physical, chemical, and molecular mechanisms that underlie basic properties of biological membranes and mediate membrane-related cellular functions. The primary topics of the journal are membrane structure, mechanisms of membrane transport, bioenergetics and photobiology, intracellular signaling as well as membrane aspects of cell biology, immunology, and medicine. The journal is multidisciplinary and gives preference to those articles that employ a variety of experimental approaches, basically in biophysics but also in biochemistry, cytology, and molecular biology. The journal publishes articles that strive for unveiling membrane and cellular functions through innovative theoretical models and computer simulations.
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