microrna作为口腔疾病的生物标志物

Q2 Medicine Singapore Dental Journal Pub Date : 2015-12-01 DOI:10.1016/j.sdj.2015.09.001

Su-Hwan Kim , Su-Yeon Lee , Yong-Moo Lee , Young-Kyoo Lee

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引用次数: 17

摘要

MicroRNAs (miRNAs)是一种短的非编码rna，通过介导靶基因的翻译抑制或mRNA降解，在多种生物过程中起关键调节作用。最近的研究在唾液中发现了mirna，这些mirna是有希望用作牙科疾病生物标志物的候选者。本文综述了miRNA在牙科领域的研究成果，并简要概述了目前miRNA生物标志物在牙科疾病中的进展、局限性和展望。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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MicroRNAs as biomarkers for dental diseases

MicroRNAs (miRNAs) are short, noncoding RNAs that act as key regulators of diverse biological processes by mediating translational repression or mRNA degradation of target genes. Recent studies discovered miRNAs in saliva, and these miRNAs are promising candidates for use as biomarkers of dental diseases. In this review, the results of miRNA studies in the dental field are presented, and a brief overview of the current progress, limitations, and perspectives regarding miRNA biomarkers for dental diseases is given.

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来源期刊

Singapore Dental Journal Medicine-Medicine (all)

CiteScore

2.40

自引率

0.00%

发文量

期刊介绍： The scope of the journal covers all fields related to the presentday practice of dentistry, and includes Restorative Dentistry (Operative Dentistry, Dental Materials, Prosthodontics and Endodontics), Preventive Dentistry (Periodontics, Orthodontics, Paediatric Dentistry, Public Health and Health Services), Oral Medicine, Oral Surgery and Oral Pathology. Articles pertaining to dental education and the social, political and economic aspects of dental practice are also welcomed.