{"title":"高剂量Na2-EDTA对细支气管上皮细胞增殖的影响","authors":"H. Yamaguchi, H. Usui, C. Torikata, T. Tajima","doi":"10.1016/S0014-4908(80)80003-2","DOIUrl":null,"url":null,"abstract":"<div><p>Administration of a high dose of disodium edetate (Na<sub>2</sub>-EDTA) caused an excessive proliferation of bronchiolar epithelia. This phenomenon may be related to the rapid and severe removal of fixed calcium ions from the cell surface induced by the high dose of Na<sub>2</sub>-EDTA.</p></div>","PeriodicalId":75841,"journal":{"name":"Experimentelle Pathologie","volume":"18 9","pages":"Pages 477-486"},"PeriodicalIF":0.0000,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0014-4908(80)80003-2","citationCount":"1","resultStr":"{\"title\":\"Studies on the proliferation of bronchiolar epithelia following administration of high doses of Na2-EDTA\",\"authors\":\"H. Yamaguchi, H. Usui, C. Torikata, T. Tajima\",\"doi\":\"10.1016/S0014-4908(80)80003-2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Administration of a high dose of disodium edetate (Na<sub>2</sub>-EDTA) caused an excessive proliferation of bronchiolar epithelia. This phenomenon may be related to the rapid and severe removal of fixed calcium ions from the cell surface induced by the high dose of Na<sub>2</sub>-EDTA.</p></div>\",\"PeriodicalId\":75841,\"journal\":{\"name\":\"Experimentelle Pathologie\",\"volume\":\"18 9\",\"pages\":\"Pages 477-486\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1980-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/S0014-4908(80)80003-2\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Experimentelle Pathologie\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0014490880800032\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Experimentelle Pathologie","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0014490880800032","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Studies on the proliferation of bronchiolar epithelia following administration of high doses of Na2-EDTA
Administration of a high dose of disodium edetate (Na2-EDTA) caused an excessive proliferation of bronchiolar epithelia. This phenomenon may be related to the rapid and severe removal of fixed calcium ions from the cell surface induced by the high dose of Na2-EDTA.