Dk/L与角膜缺氧:第1部分。汇率上升

Richard M Hill PhD (OD, Contributing Editor)
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引用次数: 1

摘要

最近,对更高的镜头透射率(Dk/L)的持续推动已经达到了新的成功水平。新兴的杂化材料(例如“高渗透性水凝胶”材料1)显示出100 × 10−9 (cm/sec) (mL O2/mL mm/Hg)甚至更高的Dk/Ls的潜力,与不断发展的几代刚性透气性(RGP)透镜一起,现在正在挑战“200屏障”的传输率。但是,随着这些更高的Dk/Ls,我们对角膜对更中度缺氧的反应有了更清晰的认识,以及进一步降低这些慢性水平可能需要什么样的传递性投资。
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Dk/L and corneal hypoxia: part 1. the rising rate of exchange

Recently, the ongoing drive for still higher lens transmissibilities (Dk/L) has reached new levels of success. Emerging hybrids (e.g., “highly permeable hydrogel” materials1) showing the potential for Dk/Ls of 100 × 10−9 (cm/sec) (mL O2/mL mm/Hg), and possibly higher, are joined by evolving generations of rigid gas permeable (RGP) lenses now challenging the “200 barrier” of transmissibility.2

But, with these higher Dk/Ls has come a clearer view of the cornea’s responses to more moderate realms of hypoxia and what transmissibility investments may be required to reduce those chronic levels still further.

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