抗血栓治疗是双重还是三重

Leslie Marisol Lugo , José Luis Ferreiro
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引用次数: 0

摘要

房颤患者正在接受口服抗凝药物治疗并计划进行经皮冠状动脉介入治疗的患者的抗血栓治疗管理特别复杂,主要是因为他们联合使用抗血小板和抗凝药物会增加出血风险。尽管在这种情况下缺乏可用的证据,近年来进行的一些临床试验试图评估三重抗血栓治疗(即双重抗血小板治疗加抗凝药物)和双重抗血栓治疗(即单一抗血小板药物加抗凝药物)的安全性和有效性,这两种治疗都可能基于维生素K拮抗剂或直接口服抗凝药物。本文的目的是概述目前已知的对非瓣膜性房颤进行抗凝治疗并计划经皮冠状动脉介入治疗的患者进行三联和双联抗血栓治疗的不同方法。此外,对这些患者的临床管理提出了一些实用的建议。补充信息:本文是由勃林格殷格翰公司赞助的题为“经皮冠状动脉介入治疗心房颤动患者:最新进展”的补充文章的一部分。
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Tratamiento antitrombótico doble frente a triple

The management of antithrombotic treatment in patients who are receiving oral anticoagulants for atrial fibrillation and who are scheduled for a percutaneous coronary intervention is particularly complex, mainly because they have an elevated risk of bleeding due to their combined use of antiplatelet and anticoagulant agents. Despite the lack of evidence available in this setting, a number of clinical trials carried out in recent years have attempted to evaluate the safety and efficacy of triple antithrombotic therapy (i.e. dual antiplatelet therapy plus an anticoagulant drug) and dual antithrombotic therapy (i.e. a single antiplatelet agent plus an anticoagulant drug), both potentially based on vitamin K antagonists or direct oral anticoagulants. The aim of this article was to provide an overview of what is currently known about different approaches to triple and dual antithrombotic therapy in patients who are undergoing anticoagulation for nonvalvular atrial fibrillation and who are scheduled for percutaneous coronary intervention. In addition, some practical recommendations for the clinical management of these patients are made.

Supplement information: this article is part of a supplement entitled “Treatment of patients with atrial fibrillation undergoing percutaneous coronary intervention: an update”, which is sponsored by Boehringer Ingelheim.

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来源期刊
Revista Espanola de Cardiologia Suplementos
Revista Espanola de Cardiologia Suplementos Medicine-Cardiology and Cardiovascular Medicine
CiteScore
1.20
自引率
0.00%
发文量
1
期刊介绍: Revista Española de Cardiología, is an international scientific journal dealing with cardiovascular medicine. Revista Española de Cardiología, the official publication of the Spanish Society of Cardiology, publishes research articles related to cardiovascular diseases. Articles are published in Spanish for the paper edition and in both Spanish and English in the electronic edition, which is available on the Internet. Regular sections include original articles reporting clinical or basic research, brief reports, review articles, editorials and letters to the Editor.
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