肥胖与院前心脏骤停恶化的关系

R. Vukmir
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引用次数: 3

摘要

背景。本研究评估了患者年龄、体重与院前心脏骤停生存率之间的潜在相关性,并将其作为评估碳酸氢盐对生存率影响的研究的次要终点。一项前瞻性、随机、双盲临床干预试验。研究对象为874名院前心肺骤停患者,分别来自城市、郊区和农村地区急救医疗服务(EMS)地区。该组接受常规高级心脏生命支持(ACLS)干预,随后早期给予实验性碳酸氢钠(1 mEq/L)。生存是通过ED生存的生命体征来衡量的。数据分析采用Student’st检验、Fisher’s精确检验、Pearson相关卡方和logistic回归(p<0.05)。院前骤停患者总生存率为13.9%(110 / 793)。对照组和碳酸氢盐组在患者年龄方面没有显著差异(67.7岁vs 67.4岁)。
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Association of obesity with worsened prehospital cardiac arrest
Background. This study evaluated a potential correlation between patient age, body weight and survival from prehospital cardiac arrest, as a secondary endpoint in a study evaluating the effect of bicarbonate on survival.Design. A prospective, randomized, double‐blinded clinical intervention trial.Methods. 874 prehospital cardiopulmonary arrest patients in a prehospital urban, suburban, and rural regional emergency medical service (EMS) area were used. This group underwent conventional Advanced Cardiac Life Support (ACLS) intervention followed by empiric early administration of sodium bicarbonate (1 mEq/L). Survival was measured as presence of vital signs on ED survival. Data was analyzed utilizing Student's t‐test, Fisher's exact test, Chi‐square with Pearson correlation and logistic regression (p<0.05).Results. The overall survival rate was 13.9% (110 of 793) of prehospital arrest patients. There was no significant difference between the control and bicarbonate groups for patient age (67.7 versus 67.4 ye...
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