Measurement Accuracy of Non-invasively obtained Central Systolic Blood Pressure and Central Pulse Pressure- A Systematic Review.

Review Objective To synthesise the best available research evidence on the accuracy of current non-invasive measurement methods for central systolic blood pressure and central pulse pressure. Review Question What is the accuracy of current non-invasive measurement methods for central systolic blood pressure and central pulse pressure, compared with invasive measurement techniques? Inclusion criteria Types of Participants This review will consider all studies of adult patients (18+ years old) regardless of clinical diagnosis, co-morbidities, treatments, who have been receiving measurement(s) of central SBP and/or central PP both invasively and non-invasively on the same subjects. Types of Interventions/Phenomena of Interest Studies will be considered for inclusion if the focus of the study is an examination of the accuracy of non-invasive measurement methods using applanation tonometry for central systolic blood pressure and central pulse pressure non-invasive measurement of central BP. Studies will be considered if the non-invasive central SBP and PP measurements have been compared with reference to invasively obtained values. Types of Comparator Invasive central aortic BP Measurement by a fluid-filled system and/or external pressure transducer. Types of Outcome Measures This review will consider studies that include the following types of outcome measures: means of differences between the paired measurements of a non-invasive and invasive technique, standard deviation of differences between paired measurements of a non-invasive and invasive technique, correlation coefficients of the paired measurements of a non-invasive and invasive technique, and any other measures for measurement agreement.