血友病患者对乙肝的免疫接种:比利时鲁汶血友病中心和瑞典Malmö血友病中心的联合研究。

Scandinavian journal of haematology. Supplementum Pub Date : 2009-04-24 DOI:10.1111/J.1600-0609.1984.TB02579.X

U. Hedner, B. Hansson, J. Vermylen, M. Verstraete, J. Colaert, J. Desmyter

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引用次数: 9

摘要

目前接受血浆产品治疗有感染乙型肝炎风险的出血性疾病患者(N = 30)和正常人(N = 75)接种了默沙东公司的乙型肝炎疫苗。8名血友病患者在比利时鲁汶和22名瑞典马尔默进行了免疫接种。53名对照组在鲁汶(26名s.c.和27名i.m)和22名马尔默进行了免疫接种。血友病患者的免疫原性与对照组相同，在10岁且属于对照组的个体中表现出更强的反应。很少观察到不良反应(肿胀，手臂酸痛)。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Immunization of haemophiliacs against hepatitis B. A joint study between the haemophilia centers in Leuven, Belgium and Malmö, Sweden.

Patients with bleeding disorders (N = 30) subjected to a current risk of contracting hepatitis B by treatment with plasma products as well as normal individuals (N = 75) were immunized with MSD's hepatitis B vaccine. Eight haemophiliacs were immunized in Leuven, Belgium, and 22 in Malmo, Sweden. 53 of the controls were immunized in Leuven (26 s.c. and 27 i.m.) and 22 in Malmo. The immunogenicity was the same in haemophiliacs as in the controls showing a more potent reaction in individuals 10 years old and belonged to the control group. Very few adverse reactions (swollen, sore arm) were observed.

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Scandinavian journal of haematology. Supplementum

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