一种新的“寄生”:线粒体基因组高血压

Microbe (Washington, D.C.) Pub Date : 2016-08-01 DOI:10.1128/MICROBE.11.338.1

D. Holzman

{"title":"一种新的“寄生”:线粒体基因组高血压","authors":"D. Holzman","doi":"10.1128/MICROBE.11.338.1","DOIUrl":null,"url":null,"abstract":"Mothers with a specific mutation in a mitochondrial transfer RNA (tRNA) gene may pass a predisposition to high blood pressure on to their children, according to Min-Xin Guan of Zhejiang University, Hangzhou, China, and his collaborators. The observation that hypertension within the three families studied appeared to be inherited exclusively maternally led them to suspect mitochondrial involvement, he says. Details appear in the July 2016 Molecular and Cellular Biology (doi:10.1128/MCB.00199–16).","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1128/MICROBE.11.338.1","citationCount":"0","resultStr":"{\"title\":\"A New “Parasitism”: Mitochondrial Genome-Based Hypertension\",\"authors\":\"D. Holzman\",\"doi\":\"10.1128/MICROBE.11.338.1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Mothers with a specific mutation in a mitochondrial transfer RNA (tRNA) gene may pass a predisposition to high blood pressure on to their children, according to Min-Xin Guan of Zhejiang University, Hangzhou, China, and his collaborators. The observation that hypertension within the three families studied appeared to be inherited exclusively maternally led them to suspect mitochondrial involvement, he says. Details appear in the July 2016 Molecular and Cellular Biology (doi:10.1128/MCB.00199–16).\",\"PeriodicalId\":87479,\"journal\":{\"name\":\"Microbe (Washington, D.C.)\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1128/MICROBE.11.338.1\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Microbe (Washington, D.C.)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1128/MICROBE.11.338.1\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Microbe (Washington, D.C.)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1128/MICROBE.11.338.1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

中国杭州浙江大学的管民新和他的合作者称，线粒体转移RNA (tRNA)基因发生特定突变的母亲可能会将患高血压的倾向遗传给她们的孩子。他说，观察到高血压在三个被研究的家庭中似乎完全是由母亲遗传的，这使他们怀疑线粒体的参与。详情请见2016年7月的Molecular and Cellular Biology (doi:10.1128/ MCB.00199-16)。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

A New “Parasitism”: Mitochondrial Genome-Based Hypertension

Mothers with a specific mutation in a mitochondrial transfer RNA (tRNA) gene may pass a predisposition to high blood pressure on to their children, according to Min-Xin Guan of Zhejiang University, Hangzhou, China, and his collaborators. The observation that hypertension within the three families studied appeared to be inherited exclusively maternally led them to suspect mitochondrial involvement, he says. Details appear in the July 2016 Molecular and Cellular Biology (doi:10.1128/MCB.00199–16).

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Microbe (Washington, D.C.)

自引率

0.00%

发文量