开放式胃切除术后并发症发生频率、严重程度及危险因素的识别:采用Clavien-Dindo分类对前瞻性收集的数据库进行回顾性分析。

M. Nakagawa, K. Kojima, M. Inokuchi, Keiji Kato, H. Sugita, Sho Otsuki, K. Sugihara
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引用次数: 10

摘要

本研究的目的是使用Clavien- Dindo分类来确定开放式胃切除术后并发症的频率、严重程度和危险因素,因为在以前的文章中主要使用机构特异性标准。材料和方法所有并发症资料均来自我们前瞻性收集的1999年1月至2012年12月的开放式胃切除术数据库(n=539)。并发症分为胰瘘、腹腔脓肿、吻合口漏等主要手术并发症和其他并发症。根据Clavien- Dindo分类回顾性地对频率和严重程度进行分级,以便后续分析危险因素。结果156例患者共发生222起事件,占28.9%。IIIa级及以上并发症在主要手术并发症中占8.3%,在所有并发症中占10.6%。死亡率为1.1%。失血是IIIa级及以上主要手术并发症的唯一独立危险因素(优势比1.923,95%可信区间0.320 ~ 0.786,p=0.003)。全胃切除术是所有IIIa级及以上并发症的唯一独立危险因素(优势比2.075,95%可信区间0.260-0.896,p=0.021)。本研究对开放式胃切除术后的并发症进行了客观的综述。出血和全胃切除术是发生并发症的重要危险因素。
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Identification of frequency, severity and risk factors of complications after open gastrectomy: Retrospective analysis of prospectively collected database using the Clavien-Dindo classification.
Introduction The purpose of this study was to identify the frequency, severity, and risk factors of complications after open gastrectomy using the Clavien- Dindo classification because institution-specific criteria were mostly used in the previous articles. Materials and Methods All complication data were obtained from our prospectively collected database of open gastrectomy from January 1999 to December 2012 (n=539). Complications were classified into either major surgical complications such as pancreatic fistula, abdominal abscess, and anastomotic leakage, or others. Frequency and severity were graded retrospectively according to the Clavien- Dindo classification for subsequent analysis of risk factors. Results There were 222 events occurred in 156 patients (28.9%). Complications of grade IIIa or greater were 8.3% for major surgical complications and 10.6% for all complications. The mortality rate was 1.1%. Blood loss was the only independent risk factor for major surgical complications of grade IIIa or greater (odds ratio 1.923, 95% Confidence Interval 0.320-0.786, p=0.003). Total gastrectomy was the only independent risk factor for all complications of grade IIIa or greater (Odds ratio 2.075, 95% Confidence Interval 0.260-0.896, p=0.021). Disscussion The present study provided the objective overview regarding complications after open gastrectomy. Blood loss and total gastrectomy were revealed as the significant risk factors for complications.
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来源期刊
Journal of Medical and Dental Sciences
Journal of Medical and Dental Sciences Dentistry-Dentistry (all)
CiteScore
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期刊介绍: "Journal of Medical and Dental Sciences" publishes the results of research conducted at Tokyo Medical and Dental University. The journal made its first appearance in 1954. We issue four numbers by the year.
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