取代3,4-二烷基-2,6-二芳基-胡椒碱-4-醇衍生物的合成及其构象研究

T. Maruthavanan, P. Venkatesan
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引用次数: 0

摘要

报道了用格氏试剂还原顺式-3-烷基-2,6-二芳基哌啶-4-酮(1-6),合成一系列3,4-二烷基-2,6-二芳基哌啶-4-醇衍生物(7-12)。根据光谱数据对合成的杂环进行了表征,并对其构象进行了讨论。
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Synthesis of Substituted 3,4-Dialkyl-2,6-Diaryl- Piperidin-4-ol Derivatives and Their Conformational Study
The synthesis of series of 3,4-dialkyl-2,6-diaryl-piperidin-4-ol derivatives (7-12) by reduction of cis-3-alkyl-2,6-diarylpiperidin-4-one (1-6) using Grignard reagent has been reported. The synthesized heterocycles have been characterized on basis of spectroscopic data and their conformation has also been discussed.
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E-journal of Chemistry
E-journal of Chemistry CHEMISTRY, MULTIDISCIPLINARY-
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