冠状动脉疾病病因学、遗传流行病学和药物基因组学

Q Medicine Circulation-Cardiovascular Genetics Pub Date : 2012-02-01 DOI:10.1161/CIRCGENETICS.112.962779

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引用次数: 0

摘要

以下文章被强调为循环的一部分:心血管遗传学的主题回顾系列。本系列将总结最重要的手稿，作为编辑选择，发表在循环组合和循环:心血管遗传学，特别是。本文中包含的研究代表了2010年和2011年发表的关于冠状动脉疾病主题的阅读量最大的手稿。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Coronary Artery Disease Etiology, Genetic Epidemiology, and Pharmacogenomics

The following articles are being highlighted as part of Circulation: Cardiovascular Genetics' Topic Review series. This series will summarize the most important manuscripts, as selected by the editors, published in the Circulation portfolio and Circulation: Cardiovascular Genetics, in particular. The studies included in this article represent the most read manuscripts published on the topic of coronary artery disease in 2010 and 2011.

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来源期刊

Circulation-Cardiovascular Genetics CARDIAC & CARDIOVASCULAR SYSTEMS-GENETICS & HEREDITY

CiteScore

3.95

自引率

0.00%

发文量

期刊介绍： Circulation: Genomic and Precision Medicine considers all types of original research articles, including studies conducted in human subjects, laboratory animals, in vitro, and in silico. Articles may include investigations of: clinical genetics as applied to the diagnosis and management of monogenic or oligogenic cardiovascular disorders; the molecular basis of complex cardiovascular disorders, including genome-wide association studies, exome and genome sequencing-based association studies, coding variant association studies, genetic linkage studies, epigenomics, transcriptomics, proteomics, metabolomics, and metagenomics; integration of electronic health record data or patient-generated data with any of the aforementioned approaches, including phenome-wide association studies, or with environmental or lifestyle factors; pharmacogenomics; regulation of gene expression; gene therapy and therapeutic genomic editing; systems biology approaches to the diagnosis and management of cardiovascular disorders; novel methods to perform any of the aforementioned studies; and novel applications of precision medicine. Above all, we seek studies with relevance to human cardiovascular biology and disease. Manuscripts are examined by the editorial staff and usually evaluated by expert reviewers assigned by the editors. Both clinical and basic articles will also be subject to statistical review, when appropriate. Provisional or final acceptance is based on originality, scientific content, and topical balance of the journal. Decisions are communicated by email, generally within six weeks. The editors will not discuss a decision about a manuscript over the phone. All rebuttals must be submitted in writing to the editorial office.