Juliana Paes Leme de Mello Sousa, R. N. Oliveira, Antonia Monica Neres Santos, O. Gamallo, Leonardo Sales Araújo, A. Middea, Y. P. Cid, Rosane Nora Castro
{"title":"负载蜂胶的高吸水性可生物降解CMC膜:Peppas-Sahlin动力学释放","authors":"Juliana Paes Leme de Mello Sousa, R. N. Oliveira, Antonia Monica Neres Santos, O. Gamallo, Leonardo Sales Araújo, A. Middea, Y. P. Cid, Rosane Nora Castro","doi":"10.1590/0104-1428.20230010","DOIUrl":null,"url":null,"abstract":"Propolis is a resinous product collected by honeybees with a complex chemical composition. Sodium carboxymethylcellulose is a polymer commonly used in wound care. The goal of the present work was to produce and characterize NaCMC membranes loaded with extract of Brazilian brown propolis (CMC-P). Flavonoids and phenolic acids were identified in the propolis extracts, where the main identified substance was kaempferide. The brown propolis extracted was active against S. aureus . The low swelling capacity and high gel fraction of CMC-P would be the consequence of propolis (responsible for a hydrophobic barrier) filling the pores of the membrane. Propolis could be anchoring the NaCMC chains (as observed by FTIR) due to interaction between components, which is corroborated by the CMC-P sample degrading less than the CMC sample (>400ºC). There was non-linear diffusion release kinetics for most phenolic substances of the propolis extract. The CMC-P sample presents potential as a dressing material.","PeriodicalId":20282,"journal":{"name":"Polimeros-ciencia E Tecnologia","volume":"1 1","pages":""},"PeriodicalIF":1.0000,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Superabsorbent biodegradable CMC membranes loaded with propolis: Peppas-Sahlin kinetics release\",\"authors\":\"Juliana Paes Leme de Mello Sousa, R. N. Oliveira, Antonia Monica Neres Santos, O. Gamallo, Leonardo Sales Araújo, A. Middea, Y. P. Cid, Rosane Nora Castro\",\"doi\":\"10.1590/0104-1428.20230010\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Propolis is a resinous product collected by honeybees with a complex chemical composition. Sodium carboxymethylcellulose is a polymer commonly used in wound care. The goal of the present work was to produce and characterize NaCMC membranes loaded with extract of Brazilian brown propolis (CMC-P). Flavonoids and phenolic acids were identified in the propolis extracts, where the main identified substance was kaempferide. The brown propolis extracted was active against S. aureus . The low swelling capacity and high gel fraction of CMC-P would be the consequence of propolis (responsible for a hydrophobic barrier) filling the pores of the membrane. Propolis could be anchoring the NaCMC chains (as observed by FTIR) due to interaction between components, which is corroborated by the CMC-P sample degrading less than the CMC sample (>400ºC). There was non-linear diffusion release kinetics for most phenolic substances of the propolis extract. The CMC-P sample presents potential as a dressing material.\",\"PeriodicalId\":20282,\"journal\":{\"name\":\"Polimeros-ciencia E Tecnologia\",\"volume\":\"1 1\",\"pages\":\"\"},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2023-09-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Polimeros-ciencia E Tecnologia\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1590/0104-1428.20230010\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"POLYMER SCIENCE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Polimeros-ciencia E Tecnologia","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1590/0104-1428.20230010","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"POLYMER SCIENCE","Score":null,"Total":0}
Superabsorbent biodegradable CMC membranes loaded with propolis: Peppas-Sahlin kinetics release
Propolis is a resinous product collected by honeybees with a complex chemical composition. Sodium carboxymethylcellulose is a polymer commonly used in wound care. The goal of the present work was to produce and characterize NaCMC membranes loaded with extract of Brazilian brown propolis (CMC-P). Flavonoids and phenolic acids were identified in the propolis extracts, where the main identified substance was kaempferide. The brown propolis extracted was active against S. aureus . The low swelling capacity and high gel fraction of CMC-P would be the consequence of propolis (responsible for a hydrophobic barrier) filling the pores of the membrane. Propolis could be anchoring the NaCMC chains (as observed by FTIR) due to interaction between components, which is corroborated by the CMC-P sample degrading less than the CMC sample (>400ºC). There was non-linear diffusion release kinetics for most phenolic substances of the propolis extract. The CMC-P sample presents potential as a dressing material.
期刊介绍:
Polímeros is a quarterly publication of the Associação Brasileira de Polímeros - ABPol (Brazilian Polymer Association), which publishes Review Articles, Original Articles and Short Communications, disclosing advances in the knowledge of Polymer Science and Technology.