М. А. Рубанский, Анатолий Петрович Казанцев, П. А. Керимов, О. А. Кириллова, Светлана Николаевна Михайлова, А. С. Тёмный, Е. В. Шарапова, М. В. Рубанская
{"title":"6岁以下患者肾细胞癌:罕见的临床观察","authors":"М. А. Рубанский, Анатолий Петрович Казанцев, П. А. Керимов, О. А. Кириллова, Светлана Николаевна Михайлова, А. С. Тёмный, Е. В. Шарапова, М. В. Рубанская","doi":"10.15690/ONCO.V5I4.1971","DOIUrl":null,"url":null,"abstract":"Background . According to the data of the world literature and own data of observations renal cell carcinoma (RCC) in children is a rare pathology. There are mainly localized and locally common forms of the disease, characterized by a good prognosis and rare reccurence. The tactic of the treatment in this group of patients based on radical surgery. If there are distant metastases, adjuvant chemotherapy is performed. The drug of choice in metastatic forms is a tyrosine kinase ingibitor. Description of a Clinical Case . A review of the world literature on the problem of RCC in children and also the clinical observation of RCC in a 6 years old patient, who treated in N.N. Blokhin National Medical Research Center of Oncology (Moscow), are presented. Now the patient is healthy and is under the dynamic observation. Conclusion . The rarity of RCС requires careful examination and observation of patients, morphological and molecular-genetic study of the tumor for features of biology and develop of «adult» cancer in children.","PeriodicalId":37249,"journal":{"name":"Onkopediatria","volume":"5 1","pages":"278-283"},"PeriodicalIF":0.0000,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Почечно-клеточный рак у пациентки в возрасте 6 лет: редкое клиническое наблюдение\",\"authors\":\"М. А. Рубанский, Анатолий Петрович Казанцев, П. А. Керимов, О. А. Кириллова, Светлана Николаевна Михайлова, А. С. Тёмный, Е. В. Шарапова, М. В. Рубанская\",\"doi\":\"10.15690/ONCO.V5I4.1971\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background . According to the data of the world literature and own data of observations renal cell carcinoma (RCC) in children is a rare pathology. There are mainly localized and locally common forms of the disease, characterized by a good prognosis and rare reccurence. The tactic of the treatment in this group of patients based on radical surgery. If there are distant metastases, adjuvant chemotherapy is performed. The drug of choice in metastatic forms is a tyrosine kinase ingibitor. Description of a Clinical Case . A review of the world literature on the problem of RCC in children and also the clinical observation of RCC in a 6 years old patient, who treated in N.N. Blokhin National Medical Research Center of Oncology (Moscow), are presented. Now the patient is healthy and is under the dynamic observation. Conclusion . The rarity of RCС requires careful examination and observation of patients, morphological and molecular-genetic study of the tumor for features of biology and develop of «adult» cancer in children.\",\"PeriodicalId\":37249,\"journal\":{\"name\":\"Onkopediatria\",\"volume\":\"5 1\",\"pages\":\"278-283\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-12-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Onkopediatria\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15690/ONCO.V5I4.1971\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Onkopediatria","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15690/ONCO.V5I4.1971","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
Почечно-клеточный рак у пациентки в возрасте 6 лет: редкое клиническое наблюдение
Background . According to the data of the world literature and own data of observations renal cell carcinoma (RCC) in children is a rare pathology. There are mainly localized and locally common forms of the disease, characterized by a good prognosis and rare reccurence. The tactic of the treatment in this group of patients based on radical surgery. If there are distant metastases, adjuvant chemotherapy is performed. The drug of choice in metastatic forms is a tyrosine kinase ingibitor. Description of a Clinical Case . A review of the world literature on the problem of RCC in children and also the clinical observation of RCC in a 6 years old patient, who treated in N.N. Blokhin National Medical Research Center of Oncology (Moscow), are presented. Now the patient is healthy and is under the dynamic observation. Conclusion . The rarity of RCС requires careful examination and observation of patients, morphological and molecular-genetic study of the tumor for features of biology and develop of «adult» cancer in children.