6岁以下患者肾细胞癌:罕见的临床观察

Q3 Medicine Onkopediatria Pub Date : 2018-12-30 DOI:10.15690/ONCO.V5I4.1971
М. А. Рубанский, Анатолий Петрович Казанцев, П. А. Керимов, О. А. Кириллова, Светлана Николаевна Михайлова, А. С. Тёмный, Е. В. Шарапова, М. В. Рубанская
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引用次数: 0

摘要

背景。根据国际文献资料及本人观察资料,儿童肾细胞癌(RCC)是一种罕见的病理。本病主要有局限性和局部常见形式,特点是预后好,很少复发。这组患者的治疗策略是根治性手术。如果有远处转移,则进行辅助化疗。转移形式的首选药物是酪氨酸激酶激活剂。临床病例描述。本文对世界上关于儿童肾细胞癌的文献进行了综述,并对1例6岁儿童肾细胞癌的临床观察进行了综述,该患者在莫斯科的Blokhin国家肿瘤医学研究中心接受治疗。目前患者身体健康,正在接受动态观察。结论。RCС的罕见性需要对患者进行仔细的检查和观察,对肿瘤的生物学特征和“成人”癌症在儿童中的发展进行形态学和分子遗传学研究。
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Почечно-клеточный рак у пациентки в возрасте 6 лет: редкое клиническое наблюдение
Background . According to the data of the world literature and own data of observations renal cell carcinoma (RCC) in children is a rare pathology. There are mainly localized and locally common forms of the disease, characterized by a good prognosis and rare reccurence. The tactic of the treatment in this group of patients based on radical surgery. If there are distant metastases, adjuvant chemotherapy is performed. The drug of choice in metastatic forms is a tyrosine kinase ingibitor. Description of a Clinical Case . A review of the world literature on the problem of RCC in children and also the clinical observation of RCC in a 6 years old patient, who treated in N.N. Blokhin National Medical Research Center of Oncology (Moscow), are presented. Now the patient is healthy and is under the dynamic observation. Conclusion . The rarity of RCС requires careful examination and observation of patients, morphological and molecular-genetic study of the tumor for features of biology and develop of «adult» cancer in children.
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Onkopediatria
Onkopediatria Medicine-Pediatrics, Perinatology and Child Health
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