2'-脱氧克福霉素和其他腺苷脱氨酶抑制剂

Reviews on drug metabolism and drug interactions Pub Date : 1980-01-01 DOI:10.1515/DMDI.1980.3.1-2.105

R. Glazer

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引用次数: 5

摘要

全面回顾了腺苷脱氨酶抑制剂的药理学性质及其与腺苷代谢物和类似物的相互作用。我把重点放在这类药物的治疗效用上，而不是它们在腺苷脱氨酶动力学方面的作用机制，希望这篇综述将为该领域进一步的药物开发提供一个更有用的框架，并作为当前和未来的参考

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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2'-DEOXYCOFORMYCIN AND OTHER ADENOSINE DEAMINASE INHIBITORS

A comprehensive review of the pharmacological properties o f adenosine deaminase inhibitors and their interaction with adenosine metabolites and analogs is presented. I have concentrated upon the therapeutic utility o f this class of drugs, rather than upon their mechanism of action with respect to the kinetics o f adenosine deaminase, in the hope that this review will serve as a more useful framework for further drug development in this field, and as a reference for current and future

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Reviews on drug metabolism and drug interactions

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