生物聚合物涂层生物活性玻璃上磷灰石的增强沉淀

Q1 Materials Science Biomedical Glasses Pub Date : 2015-10-20 DOI:10.1515/bglass-2015-0011
M. Araújo, M. Miola, A. Venturello, G. Baldi, J. Pérez, E. Verné
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引用次数: 3

摘要

摘要本研究采用生物相容性天然聚合物浸渍法制备硅基生物活性玻璃颗粒,研究有机涂层对玻璃生物活性的影响。烧结工艺优化后,在模拟体液(SBF)中浸泡后,通过扫描电镜、能谱分析(SEM, EDS)、x射线衍射(XRD)、傅里叶变换红外光谱(FT-IR)和pH测量对未包覆和包覆微球进行了表征。在生物聚合物存在的情况下,样品在SBF中浸泡时磷灰石形成能力增强,pH控制更好。这一结果为简单制造用于医疗应用的高生物活性无机-有机杂化材料提供了新的见解。
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Enhanced apatite precipitation on a biopolymer-coated bioactive glass
Abstract In this work, sintered pellets of a silica-based bioactive glass were dip-coated with a biocompatible natural-derived polymer in order to investigate the influence of the organic coating on the glass bioactivity. After the sintering process optimization, uncoated and coated pellets have been characterized by means of scanning electron microscopy with energy dispersive spectroscopy (SEM, EDS), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR) and pH measurements, after the immersion in a simulated body fluid (SBF). An increased apatite forming ability and a better control of the pH during soaking of the samples in SBF were observed in the presence of the biopolymer. This result opens a new insight on the simple fabrication of highly bioactive hybrid inorganic-organic materials for medical applications.
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来源期刊
Biomedical Glasses
Biomedical Glasses Materials Science-Surfaces, Coatings and Films
自引率
0.00%
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审稿时长
17 weeks
期刊介绍: Biomedical Glasses is an international Open Access-only journal covering the field of glasses for biomedical applications. The scope of the journal covers the science and technology of glasses and glass-based materials intended for applications in medicine and dentistry. It includes: Chemistry, physics, structure, design and characterization of biomedical glasses Surface science and interactions of biomedical glasses with aqueous and biological media Modeling structure and reactivity of biomedical glasses and their interfaces Biocompatibility of biomedical glasses Processing of biomedical glasses to achieve specific forms and functionality Biomedical glass coatings and composites In vitro and in vivo evaluation of biomedical glasses Glasses and glass-ceramics in engineered regeneration of tissues and organs Glass-based devices for medical and dental applications Application of glasses and glass-ceramics in healthcare.
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