心外膜脂肪组织在诱发和维持心房颤动中的作用

IF 0.9 4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Cardiovascular Innovations and Applications Pub Date : 2022-01-01 DOI:10.15212/cvia.2022.0012
Ye Tian
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引用次数: 3

摘要

心房颤动是导致心源性中风最常见的心律失常。心外膜脂肪组织与心房心肌之间无膜状结构,心外膜脂肪组织直接覆盖心房心肌表面。心外膜脂肪组织炎症微环境的形成、纤维化、心外膜脂肪组织浸润、自主神经功能障碍和氧化应激是诱发和维持心房颤动的重要机制。本文将对这些机制进行综述。
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Role of Epicardial Adipose Tissue in Triggering and Maintaining Atrial Fibrillation
Atrial fibrillation is the most common arrhythmia leading to cardiogenic stroke. Without membranous sructure betweenepicardial adipose tissue and atrial myocardium, epicardial adipose tissue directly covers the surface of the atrial myocardium.The formation of an epicardial adipose tissue inflammatory microenvironment, fibrosis, infiltration by epicardialadipose tissue, autonomic dysfunction and oxidative stress are important mechanisms that trigger and maintainatrial fibrillation. Those mechanisms are reviewed herein.
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来源期刊
Cardiovascular Innovations and Applications
Cardiovascular Innovations and Applications CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
0.80
自引率
20.00%
发文量
222
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