{"title":"牛白血病病毒野外分离株长末端重复序列的遗传多样性","authors":"A. Pluta, M. Rola-Łuszczak, M. Olech, J. Kuźmak","doi":"10.1515/BVIP-2015-0065","DOIUrl":null,"url":null,"abstract":"Abstract In this study the sequences of the long terminal repeat (LTR) of field isolates of the bovine leukaemia virus (BLV) were analysed. These isolates came from emerging cases of BLV infection in cattle from herds having BLV-free status. We found several sequence variations within regulatory motifs in the LTRs like GRE, DAS and interferon binding site. These mutations can possibly affect transcriptional activity of the virus, leading to its silencing.","PeriodicalId":9462,"journal":{"name":"Bulletin of The Veterinary Institute in Pulawy","volume":"59 1","pages":"447 - 450"},"PeriodicalIF":0.0000,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1515/BVIP-2015-0065","citationCount":"1","resultStr":"{\"title\":\"Genetic diversity of the long terminal repeat of bovine leukaemia virus field isolates\",\"authors\":\"A. Pluta, M. Rola-Łuszczak, M. Olech, J. Kuźmak\",\"doi\":\"10.1515/BVIP-2015-0065\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Abstract In this study the sequences of the long terminal repeat (LTR) of field isolates of the bovine leukaemia virus (BLV) were analysed. These isolates came from emerging cases of BLV infection in cattle from herds having BLV-free status. We found several sequence variations within regulatory motifs in the LTRs like GRE, DAS and interferon binding site. These mutations can possibly affect transcriptional activity of the virus, leading to its silencing.\",\"PeriodicalId\":9462,\"journal\":{\"name\":\"Bulletin of The Veterinary Institute in Pulawy\",\"volume\":\"59 1\",\"pages\":\"447 - 450\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2015-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1515/BVIP-2015-0065\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bulletin of The Veterinary Institute in Pulawy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1515/BVIP-2015-0065\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bulletin of The Veterinary Institute in Pulawy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1515/BVIP-2015-0065","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Genetic diversity of the long terminal repeat of bovine leukaemia virus field isolates
Abstract In this study the sequences of the long terminal repeat (LTR) of field isolates of the bovine leukaemia virus (BLV) were analysed. These isolates came from emerging cases of BLV infection in cattle from herds having BLV-free status. We found several sequence variations within regulatory motifs in the LTRs like GRE, DAS and interferon binding site. These mutations can possibly affect transcriptional activity of the virus, leading to its silencing.
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