Severe Gestational Transient Thyrotoxicosis: A Case Report

We present a case of gestational transient thyrotoxicosis (GTT) associated with hyperemesis gravidarum (HG) highlighting the abnormally elevated free T4 (FT4) found in this instance. This case also highlights that GTT can present as severe and symptomatic hyperthyroidism contrary to its usual presentation of subclinical or mild overt hyperthyroidism. Learning Points 1. Gestational thyrotoxicosis associated with HG can present with severe toxicosis. 2. Symptomatic treatment may be sufficient for the management of this condition. Background One of the etiologies of hyperthyroidism in pregnancy is GTT1. Typically, GTT is a mild, self-limiting condition caused by stimulation of the TSH receptor by human chorionic gonadotropin (hCG).