慢性精神病患者的炎症:中性粒细胞/次磷酸盐、血小板/次磷酸盐比率和平均血栓形成率

Figen UNAL DEMİR, Filiz Özsoy, Esma AKPINAR ASLAN
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引用次数: 0

摘要

目的:研究i型轴精神疾病患者中性粒细胞/淋巴细胞比率(NLR)、血小板/淋巴细胞比率(PLR)、平均血小板体积(MPV)、红细胞分布宽度(RDW)和白细胞水平,并与对照组进行比较。材料与方法:本研究共纳入600人,其中500人为患者,100人为对照组。其中,精神分裂症占34.8%,广发焦虑症占21%,双相情感障碍占14.4%,重性抑郁障碍占14%,调节障碍占7.2%,精神分裂情感障碍占4.2%,其他精神疾病占3.6%。结果:组间血红蛋白、血小板、单核细胞、血小板分布(PCT)、RDW占比(RDW- cv)差异均无统计学意义(p值分别为0.082、0.214、0.526、0.082、0.771)。淋巴细胞、嗜酸性粒细胞、嗜碱性粒细胞、MPV、RDW标准差(RDW- sd)均高于健康对照组(p值分别为0.002、0.003、
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Kronik psikiyatri hastalarında inflamasyon: nötrofil/lenfosit, platelet/lenfosit oranları ve ortalama trombosit hacmi
Objective: The aim of this study was to examine the Neutrophil/Lymphocyte Ratio(NLR), Platelet/Lymphocyte Ratios(PLR), and Mean Platelet Volume(MPV), red blood cell distribution width(RDW) and leukocyte cell levels of patients with Axis-I psychiatric disease by comparing them with each other and healthy controls. Material and Methods: A total of 600 people were included in our study, 500 of whom were taken as the patient and 100 as the control group. The diagnosis of patients according to DSM-5-Criteria were 34.8% Schizophrenia, 21% had Generalized-Anxiety-Disorder, 14.4% had Bipolar-Affective-Disorder, 14% had Major-Depressive-Disorder, 7.2% had Adjustment-Disorder, 4.2% had Schizoaffective-Disorder, 3.6% had other psychiatric illnesses. Results: It was seen that hemoglobin, platelet, monocyte, blood platelet distribution (PCT), percentage account of RDW (RDW-CV) did not have statistically significant differences between groups (p values were 0.082, 0.214, 0.526, 0.082, 0.771, respectively). The lymphocyte, eosinophil, basophil, MPV, standard deviation of RDW (RDW-SD) were higher compared with healthy controls (p values were 0.002, 0.003,
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