肢端肥大症患者的血液学指标评估

Emek Topuz, Dilek Tüzün, Ümit Nur Özbay, Murathan Şahin
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引用次数: 0

摘要

肢端肥大症是一种慢性全身性疾病,其特征是生长激素(GH)的自主和过度分泌。肢端肥大症最常见的原因是垂体前叶的一种生长生长腺瘤。肢端肥大症的主要死亡原因是脑血管、心血管、呼吸系统疾病和恶性肿瘤。单核细胞/淋巴细胞比(MLR)、中性粒细胞/淋巴细胞比(NLR)、红细胞分布宽度(RDW)、血小板分布宽度(PDW)和δ中性粒细胞指数(DNI)是常见的炎症指标。本研究的目的是评估肢端肥大症患者治疗前后NLR、GH、RDW、MLR、PDW和DNI水平,并探讨肢端肥大症治疗对这些指标的影响。
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Akromegali Hastalarında Hematolojik İndekslerin Değerlendirilmesi
Acromegaly is a chronic systemic disease characterized by autonomous and excessive secretion of growth hormone (GH). Acromegaly is most commonly caused by ais a somatotroph adenoma of the anterior pituitary. In acromegaly, mortality primarily results from are cerebrovascular, cardiovascular, respiratory diseases and malignancies. Monocyte/lymphocyte ratio (MLR), neutrophil/lymphocyte ratio (NLR), red cell distribution width (RDW), platelet distribution width (PDW) and delta neutrophil index (DNI) are popular inflammatory markers. This study's purpose was to assess pre/post-treatment levels of NLR, GH, RDW, MLR, PDW and DNI in acromegalic patients and to investigate the impact of acromegaly treatment on these markers.
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