{"title":"基因载体在肿瘤治疗中的实际应用","authors":"Y. Sung, S. W. Kim","doi":"10.15761/ICST.1000287","DOIUrl":null,"url":null,"abstract":"Gene delivery systems for gene therapy provide a great opportunity for treating diseases from genetic disorders, cancer, and other infections. The recent development of gene delivery system has reviewed for viral delivery systems and non-viral delivery systems. The viral delivery systems have discussed for DNA-based vectors and RNA-based vectors, and the non-viral delivery systems have summarized on the bases of physical approaches and chemical methods. In the application of gene delivery systems, viral vector systems for gene therapy and polymeric gene delivery systems have briefly reviewed. *Correspondence to: Sung Wan Kim, Center for Controlled Chemical Delivery (CCCD), Department of Pharmaceutics and Pharmaceutical Chemistry, University of Utah, BPRB, Room 205, Salt Lake City, UT 84112, USA, E-mail: sw.kim@pharm.utah.edu","PeriodicalId":90850,"journal":{"name":"Integrative cancer science and therapeutics","volume":"5 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"5","resultStr":"{\"title\":\"The practical application of gene vectors in cancer therapy\",\"authors\":\"Y. Sung, S. W. Kim\",\"doi\":\"10.15761/ICST.1000287\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Gene delivery systems for gene therapy provide a great opportunity for treating diseases from genetic disorders, cancer, and other infections. The recent development of gene delivery system has reviewed for viral delivery systems and non-viral delivery systems. The viral delivery systems have discussed for DNA-based vectors and RNA-based vectors, and the non-viral delivery systems have summarized on the bases of physical approaches and chemical methods. In the application of gene delivery systems, viral vector systems for gene therapy and polymeric gene delivery systems have briefly reviewed. *Correspondence to: Sung Wan Kim, Center for Controlled Chemical Delivery (CCCD), Department of Pharmaceutics and Pharmaceutical Chemistry, University of Utah, BPRB, Room 205, Salt Lake City, UT 84112, USA, E-mail: sw.kim@pharm.utah.edu\",\"PeriodicalId\":90850,\"journal\":{\"name\":\"Integrative cancer science and therapeutics\",\"volume\":\"5 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"5\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Integrative cancer science and therapeutics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15761/ICST.1000287\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Integrative cancer science and therapeutics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15761/ICST.1000287","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 5
摘要
用于基因治疗的基因传递系统为治疗遗传性疾病、癌症和其他感染疾病提供了巨大的机会。综述了近年来基因传递系统的研究进展，包括病毒传递系统和非病毒传递系统。讨论了基于dna的载体和基于rna的载体的病毒传递系统，总结了基于物理途径和化学方法的非病毒传递系统。在基因传递系统的应用方面，综述了用于基因治疗的病毒载体系统和聚合基因传递系统。*通讯:Sung Wan Kim，受控化学输送中心，美国犹他大学药物与药物化学系，BPRB，盐湖城，UT 84112, USA, 205室，E-mail: sw.kim@pharm.utah.edu
The practical application of gene vectors in cancer therapy
Gene delivery systems for gene therapy provide a great opportunity for treating diseases from genetic disorders, cancer, and other infections. The recent development of gene delivery system has reviewed for viral delivery systems and non-viral delivery systems. The viral delivery systems have discussed for DNA-based vectors and RNA-based vectors, and the non-viral delivery systems have summarized on the bases of physical approaches and chemical methods. In the application of gene delivery systems, viral vector systems for gene therapy and polymeric gene delivery systems have briefly reviewed. *Correspondence to: Sung Wan Kim, Center for Controlled Chemical Delivery (CCCD), Department of Pharmaceutics and Pharmaceutical Chemistry, University of Utah, BPRB, Room 205, Salt Lake City, UT 84112, USA, E-mail: sw.kim@pharm.utah.edu
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
