急性发作的炎症性结肠炎与银屑病关节炎和系统性红斑狼疮在用secukinumab治疗后重叠

S. Almér, F. Faustini, Sylwester Szczegielniak, I. Gunnarsson
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引用次数: 0

摘要

收稿日期:2020年12月28日;录用日期:2021年1月05日;一名男性患者在18岁时被诊断为银屑病和银屑病关节炎,23岁时因持续性蛋白尿接受肾活检,发现免疫复合物介导的血管毛细血管肾炎伴实质肾小球硬化。抗核抗体(ANA)阴性,但抗心磷脂和γ2糖蛋白- 1抗体水平升高。
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Acute onset of inflammatory colitis in overlap with psoriatic arthritis and systemic lupus erythematosus following treatment with secukinumab
Received: December 28, 2020; Accepted: January 05, 2021; Published: January 09, 2021 A male diagnosed with psoriasis and psoriatic arthritis at age 18, underwent a kidney biopsy at age 23 due to persistent proteinuria, with findings of an immune-complex mediated mesangiocapillary nephritis with substantial glomerular sclerosis. Antinuclear antibodies (ANA) were negative but increased levels of antibodies against cardiolipin and γ2glycoprotein-I were detected.
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