以多种食物过敏为表现的急性食物蛋白性小肠结肠炎综合征1例

E. A. Filippova, N. Esakova, E. Varlamov, A. Pampura
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引用次数: 0

摘要

食物蛋白诱导的小肠结肠炎综合征(FPIES)是一种非ige介导的食物过敏,表现为胃肠道症状延迟发作(食用过敏原后1-4小时),可导致严重危及生命的疾病。由于缺乏特异性的实验室标记物来确定诱发因素并确认诊断,不明确的临床特征常常被急性肠道感染和其他胃肠道疾病所掩盖,因此在识别FPIES患者、选择正确的治疗策略和制定适当的消除饮食方面存在重大困难。本文报告一例患者自6个月大以来多次出现严重的临床表现,需要紧急住院治疗。在1.5岁时首次怀疑诊断为FPIES;随后,诊断得到临床证实,并制定了儿童进一步治疗的计划。关键词:食物蛋白性小肠结肠炎综合征(FPIES),儿童,诊断,食物过敏,诱发因素,口服食物激发试验,牛奶蛋白过敏,肉类过敏
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Clinical case of acute food-protein induced enterocolitis syndrome (FPIES) as a manifestation of multiple food allergies
Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE-mediated food allergy manifested by delayed onset of gastrointestinal symptoms (1–4 hours after allergen consumption), which can lead to severe life-threatening conditions. The absence of specific laboratory markers of FPIES allowing to determine the trigger and confirm the diagnosis, unclear clinical features often masked by acute intestinal infections and other gastrointestinal diseases create significant difficulties in identifying patients with FPIES, choosing the right tactics for their management, and prescribing an adequate elimination diet. This article presents a clinical case of a patient who had multiple episodes of severe clinical manifestations of FPIES since the age of 6 months, requiring emergency hospitalization. The diagnosis of FPIES was first suspected at the age of 1.5 years; subsequently, the diagnosis was clinically confirmed, and a plan for further management of the child was developed. Key words: food protein-induced enterocolitis syndrome (FPIES), children, diagnosis, food allergy, trigger, oral food challenge test, cow’s milk protein allergy, meat allergy
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来源期刊
Voprosy Detskoi Dietologii
Voprosy Detskoi Dietologii Medicine-Pediatrics, Perinatology and Child Health
CiteScore
1.20
自引率
0.00%
发文量
17
期刊介绍: The scientific journal Voprosy Detskoi Dietologii is included in the Scopus database. Publisher country is RU. The main subject areas of published articles are Food Science, Pediatrics, Perinatology, and Child Health, Nutrition and Dietetics, Клиническая медицина.
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