远程预处理和后处理对缺血再灌注肝损伤影响的首次论证

T. Gonçalves, V. Yamaki, João Vitor Baia Coelho, M. V. Brito, S. Percário
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引用次数: 0

摘要

缺血再灌注是一种非常常见的现象,在许多临床情况下都会出现,如肝移植以及这些器官的创伤情况。将这种损伤最小化的一种方法是心肌缺血的远程缺血过适应,即在指数缺血期间远程应用手臂或腿部短暂的非致死缺血和再灌注周期。因此,本研究旨在比较过适应和后适应对肝脏缺血再灌注损伤的影响。
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First Demonstration of the Effects of Remote Per- and Postconditioning onIschemia and Reperfusion Induced Hepatic Injury
Ischemia and reperfusion is a very frequently phenomenon that is presented in many clinical situations like in liver transplantation as well as in traumatic situation of these organs.One way of minimizing this injury is the remote ischemic perconditioning, described in myocardial ischemia, in which brief nonlethal cycles of ischemia and reperfusion of the arm or leg are applied remotely during index ischemia. Therefore, this current study aims to compare the effects of perconditioning and postconditioning on injury of ischemia and reperfusion in the liver.
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