M. Adaszyńska-Skwirzyńska, S. Zych, D. Szczerbińska
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引用次数: 2
摘要
本研究研究了恩诺沙星与薰衣草精油联合使用对3种血清型沙门氏菌的抑菌活性:肠炎沙门氏菌ATCC 13076、鸡产沙门氏菌ATCC 13036、鼠伤寒沙门菌ATCC 14028和鼠伤寒沙门菌-一种中等敏感的单菌种。采用棋盘格法对恩诺沙星与薰衣草精油的相互作用进行了分析。得到的FICI值解释如下:≤0.5时具有协同效应;> 0.5但≤1时可加;当> 1但≤4时不相互作用;bbbb4时拮抗。当分析恩诺沙星与薰衣草油的个别组合时,发现所有病例都有正的加性效应(肠炎沙门氏菌ATCC 13076 FICI - 0.85;Gallinarum biovar Pullorum ATCC 13036 FICI - 1.0;鼠伤寒沙门氏菌ATCC 14028和鼠伤寒沙门氏菌-一种中等敏感的单相菌株FICI - 0.7)。在任何情况下均未记录拮抗相互作用。当分析恩诺沙星与薰衣草油的个别组合对所测试的血清型时,在所有病例中都证明了加性效应(FIC指数:0.7-1.0)。所分析的任何组合均无拮抗作用。
In vitro antibacterial effect of enrofloxacin combined with lavender essential oil on selected Salmonella serotypes isolated most commonly poultry
The present study investigated the antimicrobial activity of enrofloxacin in combination with lavender (Lavandula angustifolia) essential oil against three serotypes of Salmonella: Salmonella Enteritidis ATCC 13076, Salmonella Gallinarum biovar Pullorum ATCC 13036, Salmonella Typhimurium ATCC 14028 and Salmonella Typhimurium – a moderately sensitive monophasic strain. The analysis of the interaction of enrofloxacin with lavender essential oil was carried out using the checkerboard method. The obtained FICI values were interpreted as follows: synergistic when ≤ 0.5; additive when > 0.5 but ≤ 1; non-interactive when > 1 but ≤ 4; antagonistic when > 4. When analysing individual combinations of enrofloxacin with lavender oil, a positive additive effect was found in all cases (S. Enteritidis ATCC 13076 FICI – 0.85; S. Gallinarum biovar Pullorum ATCC 13036 FICI – 1.0; S. Typhimurium ATCC 14028 and S. Typhimurium – a moderately sensitive monophasic strain FICI – 0.7). Antagonistic interaction was not recorded in any case. When analysing individual combinations of enrofloxacin with lavender oil against the serotypes tested, an additive effect was demonstrated in all cases (FIC indices: 0.7-1.0). There was no antagonistic effect in any of the analysed combinations.
期刊介绍:
"Medycyna Weterynaryjna" publishes various types of articles which are grouped in the following editorial categories: reviews, original studies, scientific and professional problems, the history of veterinary medicine, posthumous memoirs, as well as chronicles that briefly relate scientific advances and developments in the veterinary profession and medicine. The most important are the first two categories, which are published with short summaries in English. Moreover, from 2001 the editors of "Medycyna Weterynaryjna", bearing in mind market demands, has also started publishing entire works in English. Since 2008 the periodical has appeared in an electronic version. The following are available in this version: summaries of studies published from 1999 to 2005, full versions of all the studies published in the years 2006-2011 (in pdf files), and full versions of the English studies published in the current year (pdf). Only summaries of the remaining studies from the current year are available. In accordance with the principles accepted by the editors, the full versions of these texts will not be made available until next year.
All articles are evaluated twice by leading Polish scientists and professionals before they are considered for publication. For years now "Medycyna Weterynaryjna" has maintained a high standard thanks to this system. The review articles are actually succinct monographs dealing with specific scientific and professional problems that are based on the most recent findings. Original works have a particular value, since they present research carried out in Polish and international scientific centers.