D. V. Frolov, V. Petrov, G. Sukhanova, D. V. Linchenko, A.E. Nalesnyi, Y. Dyachkova
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Primary Prevention of Venous Thromboembolism: Current State
The problem of primary prevention of venous thromboembolism (VTE) is currently extremely important throughout the world for various specialists, especially in general surgery, orthopedics, intensive care and therapy. Among all preventive measures, special attention should be paid to anticoagulation in acute phase of disease at the in-hospital stage and early after discharge. This review is devoted to dosage, regimen and duration of anticoagulation depending on the risk of VTEC, efficacy and safety of parenteral and oral anticoagulants. Criteria for anticoagulation dose increment or prolongation of therapy to the outpatient stage are also proposed: high and extremely high level of D-dimer with additional risk factors of VTEC, obesity, reduced motor activity in postoperative period, previous VTEC, additional Caprini scores due to a widespread new coronavirus infection. Conclusions about the need to revise the guidelines on primary prevention of VTEC are made.
期刊介绍:
Journal of Venous Disorders is a quarterly peer-reviewed medical journal. The journal highlights the key issues of prophylaxis, diagnostics and treatment of the entire spectrum of venous system diseases and their complications including acute (deep vein thrombosis, pulmonary embolism, superficial thrombophlebitis) and chronic (varicose veins, post-thrombotic syndrome, chronic venous insufficiency) pathologies as well as various lymphatic lesions (lymphedema, etc.). The new edition will encompass the whole range of topical issues including recent achievements of domestic and foreign researchers, applications of innovative technologies in the clinical practice, reviews of the literature, lectures, and results of original investigations: all that can be of interest for phlebologists, vascular surgeons, other medical specialists dealing with venous pathology in their practical work. The journal was established in 2007. The only Russian journal that reflecting a broad range of problems in diagnosis, treatment and prevention of acute and chronic venous diseases.