法尼醇治疗犬中耳炎并发厚皮马拉色菌的疗效观察

Ifarajimi R. Olabode, N. Sachivkina, E. Kiseleva, A. I. Shurov
{"title":"法尼醇治疗犬中耳炎并发厚皮马拉色菌的疗效观察","authors":"Ifarajimi R. Olabode, N. Sachivkina, E. Kiseleva, A. I. Shurov","doi":"10.22363/2312-797x-2023-18-2-250-263","DOIUrl":null,"url":null,"abstract":"The study involved 30 dogs with otitis complicated by Malassezia pachydermatis . The animals were divided into 2 groups: experimental (n = 15) and control (n = 15). The experimental group was prescribed veterinary ear drops Surolan + a solution of the drug Farnesol; the control group - Surolan. The study showed that when Farnesol is added to the treatment regimen for fungal otitis etiology in dogs, small changes in the clinical composition of the blood are recorded, characterized by an increase in the number of erythrocytes and hemoglobin, a decrease in the number of leukocytes, with a decrease in the indicators of eosinophils and rod-shaped neutrophils in the experiment compared with the control. In addition, the complete absence of Malassezia pachydermatis in the smears of the ear contents after two weeks of therapy with a combined drug was proved. That is, in the experimental group, there were no cases of the presence of yeast-like fungi (YLF) in the smear after combined therapy with Surolan + Farnesol. And in the control group of 15 animals, YLF were observed in two with microscopy of ear exudate smears, but not in high concentration. The use of a combination of Surolan and Farnesol in dogs of the experimental group led to a decrease in hyperemia, itching, edema, ear fetid fluid on the 5th7th days of treatment, and complete clinical recovery of the animals occurred by the 10th14th day of therapy. In the control group, only Surolan was used, and improvement of clinical condition occurred on days 1214, and recovery only after completion of the full course. As a result, both treatment regimens were successful, but the scheme with Farnesol gave faster results due to the wide spectrum of action of this drug: both antimicrobial and anti-inflammatory.","PeriodicalId":53086,"journal":{"name":"RUDN Journal of Agronomy and Animal Industries","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Effectiveness of Farnesol for treatment of dog otitis complicated by Malassezia pachydermatis\",\"authors\":\"Ifarajimi R. Olabode, N. Sachivkina, E. Kiseleva, A. I. Shurov\",\"doi\":\"10.22363/2312-797x-2023-18-2-250-263\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The study involved 30 dogs with otitis complicated by Malassezia pachydermatis . The animals were divided into 2 groups: experimental (n = 15) and control (n = 15). The experimental group was prescribed veterinary ear drops Surolan + a solution of the drug Farnesol; the control group - Surolan. The study showed that when Farnesol is added to the treatment regimen for fungal otitis etiology in dogs, small changes in the clinical composition of the blood are recorded, characterized by an increase in the number of erythrocytes and hemoglobin, a decrease in the number of leukocytes, with a decrease in the indicators of eosinophils and rod-shaped neutrophils in the experiment compared with the control. In addition, the complete absence of Malassezia pachydermatis in the smears of the ear contents after two weeks of therapy with a combined drug was proved. That is, in the experimental group, there were no cases of the presence of yeast-like fungi (YLF) in the smear after combined therapy with Surolan + Farnesol. And in the control group of 15 animals, YLF were observed in two with microscopy of ear exudate smears, but not in high concentration. The use of a combination of Surolan and Farnesol in dogs of the experimental group led to a decrease in hyperemia, itching, edema, ear fetid fluid on the 5th7th days of treatment, and complete clinical recovery of the animals occurred by the 10th14th day of therapy. In the control group, only Surolan was used, and improvement of clinical condition occurred on days 1214, and recovery only after completion of the full course. As a result, both treatment regimens were successful, but the scheme with Farnesol gave faster results due to the wide spectrum of action of this drug: both antimicrobial and anti-inflammatory.\",\"PeriodicalId\":53086,\"journal\":{\"name\":\"RUDN Journal of Agronomy and Animal Industries\",\"volume\":\"1 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"RUDN Journal of Agronomy and Animal Industries\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.22363/2312-797x-2023-18-2-250-263\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"RUDN Journal of Agronomy and Animal Industries","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22363/2312-797x-2023-18-2-250-263","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

这项研究涉及30只患有中耳炎并患有马拉色菌厚皮炎的狗。将动物分为实验组(n = 15)和对照组(n = 15)。试验组患者给予兽用滴耳液苏洛兰+法尼醇溶液;对照组——苏罗兰。研究表明,在治疗犬真菌性中耳炎的治疗方案中加入法尼醇后,临床血液成分发生微小变化,表现为红细胞和血红蛋白数量增加,白细胞数量减少,嗜酸性粒细胞和杆状中性粒细胞指标较对照组下降。此外,经联合用药治疗两周后,证实耳内容物涂片中完全没有厚皮马拉色菌。即实验组经苏洛兰+法尼醇联合治疗后,涂片中未出现酵母菌样真菌(YLF)。对照组15只,2只耳渗出液涂片镜检可见YLF,但浓度不高。实验组狗在治疗第5 ~ 7天使用苏洛兰和法尼醇联合用药,充血、瘙痒、水肿、耳臭液减少,治疗第10 ~ 14天临床完全恢复。在对照组中,仅使用苏洛兰,临床状况在第1214天出现改善,在完成整个疗程后才恢复。结果,两种治疗方案都取得了成功,但法尼醇方案的效果更快,因为这种药物的作用范围很广:既抗微生物又抗炎。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Effectiveness of Farnesol for treatment of dog otitis complicated by Malassezia pachydermatis
The study involved 30 dogs with otitis complicated by Malassezia pachydermatis . The animals were divided into 2 groups: experimental (n = 15) and control (n = 15). The experimental group was prescribed veterinary ear drops Surolan + a solution of the drug Farnesol; the control group - Surolan. The study showed that when Farnesol is added to the treatment regimen for fungal otitis etiology in dogs, small changes in the clinical composition of the blood are recorded, characterized by an increase in the number of erythrocytes and hemoglobin, a decrease in the number of leukocytes, with a decrease in the indicators of eosinophils and rod-shaped neutrophils in the experiment compared with the control. In addition, the complete absence of Malassezia pachydermatis in the smears of the ear contents after two weeks of therapy with a combined drug was proved. That is, in the experimental group, there were no cases of the presence of yeast-like fungi (YLF) in the smear after combined therapy with Surolan + Farnesol. And in the control group of 15 animals, YLF were observed in two with microscopy of ear exudate smears, but not in high concentration. The use of a combination of Surolan and Farnesol in dogs of the experimental group led to a decrease in hyperemia, itching, edema, ear fetid fluid on the 5th7th days of treatment, and complete clinical recovery of the animals occurred by the 10th14th day of therapy. In the control group, only Surolan was used, and improvement of clinical condition occurred on days 1214, and recovery only after completion of the full course. As a result, both treatment regimens were successful, but the scheme with Farnesol gave faster results due to the wide spectrum of action of this drug: both antimicrobial and anti-inflammatory.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
34
审稿时长
12 weeks
期刊最新文献
Impact of fungicides on potato pathogen in the Tambov region of the Russian Federation Cytological and microbiotic aspects of the diagnosis of otitis externa in dogs Allelic frequency of beta-lactoglobulin gene in different cattle breeds Features of growing new cultivars of annual flowering plants in Kola Subarctic Efficacy of COP-based protocol used with raltegravir in treatment of cats with mediastinal lymphoma and progressive viral leukemia
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1