肥厚型心肌病猫肝心综合征的病程特点

E. Sotnikova, Olesya A. Petrukhina, V. Byakhova, Vladimir D. Sibirtsev
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摘要

研究了在肥厚性心肌病背景下形成的肝心综合征猫的临床、实验室和仪器参数的变化问题。众所周知,在患有充血性心力衰竭的高级猫中,继发性肝病可以发展和进展。研究表明,在肥厚性心肌病患者总数(n = 83)中,33.7%的猫发生肝心综合征。已经确定,猫的肝心并发症是肥厚性心肌病更严重病程的危险因素。患有肥厚性心肌病的猫的肝心综合征的特征是严重的体温过低,循环和呼吸衰竭。在患病动物中,睡眠时呼吸频率增加(33.39.3次/分钟vs 17.91.8次/分钟;p 0.001)。患有肝心综合征的家猫平均动脉血压下降(100.219.3 vs 107.219.1 mm Hg;P 0.05),窦性心动过速(200.319.6 17.8次/min;p 0.001),这导致PQ间隔显著降低(57.99.9 ms vs 64.99.9 ms;p 0.001)和QT间期(168.917,2 vs 157.518.6 ms;p 0.001)。病猫毛细血管充血时间明显增加,室内传导减慢,心电图室房复合电压升高,肺静脉扩张,左心房明显扩张,左心室极度同心肥厚,左心室心肌横向收缩力增加,左右心室纵向收缩力下降。心肌细胞溶解综合征,胆汁淤积和低白蛋白血症
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Features of the course of hepatocardial syndrome in cats with hypertrophic cardiomyopathy
The issues of changes in clinical, laboratory and instrumental parameters in cats with hepatocardial syndrome formed against the background of hypertrophic cardiomyopathy were studied. It is known that in high-bred cats with congestive heart failure, secondary hepatopathy can develop and progress. It was shown that hepatocardial syndrome occurs in 33.7 % of cats, out of the total number of patients with hypertrophic cardiomyopathy (n = 83). It has been established that hepatocardial complications in cats are a risk factor for a more severe course of hypertrophic cardiomyopathy. Hepatocardial syndrome in cats with hypertrophic cardiomyopathy is characterized by severe hypothermia, circulatory and respiratory failure. In sick animals, an increase in frequency of breathing during sleep was recorded (33.39.3 versus 17.91.8 times/min; p 0.001). Domestic cats with hepatocardial syndrome had a decrease in mean arterial blood pressure (100.219.3 versus 107.219.1 mm Hg; p 0.05), sinus tachycardia (200.319.6 17.8 times/min; p 0.001), which leads to a significant decrease in PQ intervals (57.99.9 versus 64.99.9 ms; p 0.001) and QT intervals (168.917, 2 vs 157.518.6 ms; p 0.001). Sick cats had a significant increase in the time of refilling of capillaries with blood, slowdown in intraventricular conduction, increase in voltage of ventricular and atrial complex on electrocardiograms, expansion of pulmonary vein, significant dilatation of left atrium, extreme concentric hypertrophy of left ventricle, increase in transverse contractility of myocardium of left ventricle and decrease in longitudinal contractility myocardium of left and right ventricles, cardiomyocyte cytolysis syndrome, cholestasis, and hypoalbuminemia
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审稿时长
12 weeks
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