可增加吸收性的海绵骨替代物的制造

IF 0.5 4区工程技术 Q4 ENGINEERING, CHEMICAL Chemical and Process Engineering-Inzynieria Chemiczna I Procesowa Pub Date : 2023-11-06 DOI:10.24425/cpe.2019.130215

Monika Budnicka, Agnieszka Gadomska‐Gajadhur, Paweł Ruśkowski

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引用次数: 2

摘要

采用冷冻提取法制备亲水性增强的复合支架用于松质骨再生。采用聚l -丙交酯(PLLA)作为建筑材料。甲基丙烯酸共聚物(商品名Eudragit®)是一种亲水性改性剂。对该工艺进行了初步研究和优化。对于获得的支架，确定Eudragit®E100/PLLA重量比影响的回归方程;计算甲醇(孔团)/PLLA溶液在二氧六环中的体积比对互连孔隙率的影响以及获得的植入物的质量可吸收性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Manufacturing of substitutes for spongy bone with increased absorbability

Composite scaffolds with increased hydrophilicity were prepared for cancellous bone regeneration by the freeze-extraction method. As a construction material, a poly–L–lactide (PLLA) was applied. As a hydrophilic, modifying agent a methacrylic acid copolymer, trade name Eudragit®, was used. A preliminary investigation and optimization of the process were performed. For the obtained scaffolds, regression equations determining the effect of: Eudragit®E100/PLLA weight ratio; volume ratio of methanol (porophore)/PLLA solution in dioxane on interconnected porosity and mass absorbability of obtained implants were calculated.

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来源期刊

Chemical and Process Engineering-Inzynieria Chemiczna I Procesowa 工程技术-工程：化工

CiteScore

1.30

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The content, aim and scope of the proposals should comply with the main subject of the journal, i.e. they should deal with mathematical modelling and/or experimental investigations on momentum, heat and mass transfer, unit processes and operations, integrated processes, biochemical engineering, statics and kinetics of chemical reactions. The experiments and modelling may cover different scales and processes ranging from the molecular phenomena up to production systems. The journal language is grammatically correct British English. Chemical and Process Engineering publishes: i) full text research articles, ii) invited reviews, iii) letters to the editor and iv) short communications, aiming at important new results and/or applications. Each of the publication form is peer-reviewed by at least two independent referees.