五肽BPC157对索他洛尔所致Wistar Albino大鼠血液动力学和心电图异常的影响

Q4 Medicine Lijecnicki vjesnik Pub Date : 2023-04-23 DOI:10.26800/lv-145-supl2-bs01

Marjeta Linarić Lipnjak, Matija Lacković, H. M. Chiddenton

{"title":"五肽BPC157对索他洛尔所致Wistar Albino大鼠血液动力学和心电图异常的影响","authors":"Marjeta Linarić Lipnjak, Matija Lacković, H. M. Chiddenton","doi":"10.26800/lv-145-supl2-bs01","DOIUrl":null,"url":null,"abstract":"were noted, along with the decrease in abdominal aortic pressure (52 ± 2 mmHg). These effects were attenuated in BPC treated animals (-2 ± 1 mmHg for superior sagittal sinus, 6 ± 1 mmHg in portal vein, 5 ± 1 mmHg in inferior caval vein, and 83 ± 2 mmHg in abdominal aorta). CONCLUSION: In summary, BPC 157 attenuated detrimental hemodynamic effects of sotalol while the effects on ECG parameters were also noted, but not as lasting, as hemodynamic ones, supporting the view of BPC 157 as a rapid-acting protective agent.","PeriodicalId":18134,"journal":{"name":"Lijecnicki vjesnik","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Effect of Pentadecapeptide BPC 157 on Hemodynamic and ECG Disorders Caused by Sotalol in Wistar Albino Rats\",\"authors\":\"Marjeta Linarić Lipnjak, Matija Lacković, H. M. Chiddenton\",\"doi\":\"10.26800/lv-145-supl2-bs01\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"were noted, along with the decrease in abdominal aortic pressure (52 ± 2 mmHg). These effects were attenuated in BPC treated animals (-2 ± 1 mmHg for superior sagittal sinus, 6 ± 1 mmHg in portal vein, 5 ± 1 mmHg in inferior caval vein, and 83 ± 2 mmHg in abdominal aorta). CONCLUSION: In summary, BPC 157 attenuated detrimental hemodynamic effects of sotalol while the effects on ECG parameters were also noted, but not as lasting, as hemodynamic ones, supporting the view of BPC 157 as a rapid-acting protective agent.\",\"PeriodicalId\":18134,\"journal\":{\"name\":\"Lijecnicki vjesnik\",\"volume\":\"1 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-04-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Lijecnicki vjesnik\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.26800/lv-145-supl2-bs01\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Lijecnicki vjesnik","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.26800/lv-145-supl2-bs01","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

摘要

腹主动脉压下降(52±2 mmHg)。这些影响在BPC处理的动物中减弱(上矢状窦-2±1mmhg，门静脉6±1mmhg，下腔静脉5±1mmhg，腹主动脉83±2mmhg)。结论:综上所述，bpc157减轻了索他洛尔的有害血流动力学影响，同时也注意到对心电图参数的影响，但不像血流动力学那样持久，支持bpc157作为速效保护剂的观点。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

Effect of Pentadecapeptide BPC 157 on Hemodynamic and ECG Disorders Caused by Sotalol in Wistar Albino Rats

were noted, along with the decrease in abdominal aortic pressure (52 ± 2 mmHg). These effects were attenuated in BPC treated animals (-2 ± 1 mmHg for superior sagittal sinus, 6 ± 1 mmHg in portal vein, 5 ± 1 mmHg in inferior caval vein, and 83 ± 2 mmHg in abdominal aorta). CONCLUSION: In summary, BPC 157 attenuated detrimental hemodynamic effects of sotalol while the effects on ECG parameters were also noted, but not as lasting, as hemodynamic ones, supporting the view of BPC 157 as a rapid-acting protective agent.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Lijecnicki vjesnik Medicine-Medicine (all)

CiteScore

0.20

自引率

0.00%

发文量

117