V. Smolyannikova, A. Karamova, A. Vorontsova, L. F. Znamenskaya, M. Nefedova, K. M. Aulova
{"title":"蕈样真菌病与牛皮癣鉴别诊断中的问题:临床与形态学特征的比较","authors":"V. Smolyannikova, A. Karamova, A. Vorontsova, L. F. Znamenskaya, M. Nefedova, K. M. Aulova","doi":"10.31088/cem2022.11.3.73-80","DOIUrl":null,"url":null,"abstract":"Mycosis fungoides is an epidermotropic primary cutaneous T-cell lymphoma, represented com-posed of small and medium-sized lymphocytes with cerebriform nuclei. Differential diagnosis of cutaneous T-cell lymphoma and chronic autoimmune dermatoses, including psoriasis, may present significant chal-lenges in some cases. We analyzed three clinical cases of mycosis fungoides, in which psoriasis was initially diagnosed. Histological and immunohistochemical studies with a wide panel of antibodies (CD4 CD8, CD2, CD5, CD7, CD3) were performed, and monoclonal T-lymphocyte populations were determined with PCR. We propose an algorithm for diagnosing mycosis fungoides. Keywords: mycosis fungoides, psoriasis, morphology, immunohistochemistrycal study, diagnosis","PeriodicalId":36062,"journal":{"name":"Clinical and Experimental Morphology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Problems in differential diagnosis of mycosis fungoides and psoriasis: comparison of clinical and morphological features\",\"authors\":\"V. Smolyannikova, A. Karamova, A. Vorontsova, L. F. Znamenskaya, M. Nefedova, K. M. Aulova\",\"doi\":\"10.31088/cem2022.11.3.73-80\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Mycosis fungoides is an epidermotropic primary cutaneous T-cell lymphoma, represented com-posed of small and medium-sized lymphocytes with cerebriform nuclei. Differential diagnosis of cutaneous T-cell lymphoma and chronic autoimmune dermatoses, including psoriasis, may present significant chal-lenges in some cases. We analyzed three clinical cases of mycosis fungoides, in which psoriasis was initially diagnosed. Histological and immunohistochemical studies with a wide panel of antibodies (CD4 CD8, CD2, CD5, CD7, CD3) were performed, and monoclonal T-lymphocyte populations were determined with PCR. We propose an algorithm for diagnosing mycosis fungoides. Keywords: mycosis fungoides, psoriasis, morphology, immunohistochemistrycal study, diagnosis\",\"PeriodicalId\":36062,\"journal\":{\"name\":\"Clinical and Experimental Morphology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical and Experimental Morphology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.31088/cem2022.11.3.73-80\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical and Experimental Morphology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31088/cem2022.11.3.73-80","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
Problems in differential diagnosis of mycosis fungoides and psoriasis: comparison of clinical and morphological features
Mycosis fungoides is an epidermotropic primary cutaneous T-cell lymphoma, represented com-posed of small and medium-sized lymphocytes with cerebriform nuclei. Differential diagnosis of cutaneous T-cell lymphoma and chronic autoimmune dermatoses, including psoriasis, may present significant chal-lenges in some cases. We analyzed three clinical cases of mycosis fungoides, in which psoriasis was initially diagnosed. Histological and immunohistochemical studies with a wide panel of antibodies (CD4 CD8, CD2, CD5, CD7, CD3) were performed, and monoclonal T-lymphocyte populations were determined with PCR. We propose an algorithm for diagnosing mycosis fungoides. Keywords: mycosis fungoides, psoriasis, morphology, immunohistochemistrycal study, diagnosis
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
