南亚年轻女性ST段抬高型心肌梗死(STEMI)-我们应该担心吗?

S. Rehman, A. Siddiqui, Aysha Almas, Aamir Hameed Khan
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ST段抬高型心肌梗死(STEMI)——应该担心吗?背景与目的:年轻女性STEMI患者的预后较男性差。特别是南亚(SA)的此类患者的数据很少。因此,本研究探讨了这些患者的常见危险因素、血管造影特征和预后。方法:这是一项2013-2019年在巴基斯坦阿迦汗大学医院接受冠状动脉导管和血运重建术的45岁以下STEMI女性患者的横断面研究。排除有血运重建或心肌梗死的受试者。前路STEMI和PCI是最常见的血运重建模式。大多数患者(82%,n=19)为单血管病变伴左前降(LAD)病变。近端LAD病变需要27.6 (+10)mm长,平均3.0 (+0.4)mm宽的支架。1例患者死亡。三分之一的患者(n=9)表现为心力衰竭,而四分之一(n=7)表现为低血压。少数患者需要机械通气、心肺复苏或临时起搏器。结论:STEMI在年轻SA女性中相对少见。相关的危险因素有糖尿病、肥胖和阳性家族史。SVCAD伴LAD受累是最常见的模式。死亡率、心力衰竭入院率或重复血运重建术的发生率都很低。
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Young South Asian Women with ST Elevation Myocardial Infarction (STEMI)-Should we be Worried?
ST Elevation Myocardial Infarction (STEMI)-Should Worried?. Abstract Background and Objective: Young women with STEMI fare worse than men. Data for such patients in particular South Asians (SA) is sparse. Therefore, this study explored the common risk factors, angiographic features and outcomes in these patients. Methods: It was a cross-sectional study done from 2013-2019 on female STEMI patients <45 years who underwent Coronary Catheterization and revascularization at Aga Khan University Hospital, Pakistan. Subjects with revascularizations or MI were excluded. with Anterior STEMI and PCI was the commonest mode of revascularization. Majority, (82%, n=19) had Single vessel disease with lesions in Left Anterior Descending (LAD). Proximal LAD lesions required stents 27.6 (+10) mm long and 3.0 (+0.4) mm wide on average. Mortality was seen in one patient. A third of patients (n=9) presented with heart failure whereas a quarter (n=7) with hypotension. A minority required mechanical ventilation, Cardiopulmonary resuscitation or temporary pacemaker. Conclusions: STEMI is relatively uncommon in young SA women. Associated risk factors are Diabetes, obesity and positive family history. SVCAD with LAD involvement is the most common pattern. Rates of mortality, heart failure admissions or repeat revascularizations are minimal.
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