肝衰竭预后生物标志物的研究进展

中国综合临床 Pub Date : 2020-01-01 DOI:10.3760/CMA.J.ISSN.1008-6315.2020.01.018

J. Qiao, Rongqin Wang

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引用次数: 0

摘要

肝功能衰竭是一组发展迅速、预后危险的严重临床综合征。近年来，国内外有许多评价肝功能衰竭患者预后的生物标志物，如中性粒细胞/淋巴细胞比值、甲胎蛋白、半乳糖凝集素-3、骨桥蛋白、高尔基蛋白73、人β -防御素-1等，这些生物标志物对早期发现肝功能衰竭患者，准确评价其预后，制定有效的治疗方案具有重要意义。关键词:肝衰竭;预后;中性粒细胞/淋巴细胞比率;高尔基蛋白73;人类β-defensin-1

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Research progress in prognostic biomarkers of liver failure

Liver failure is a group of serious clinical syndrome, which develops rapidly and has a dangerous prognosis.In recent years, there are many biomarkers to evaluate the prognosis of patients with liver failure at home and abroad, such as neutrophil/lymphocyte ratio, alpha fetoprotein, galactose lectin-3, osteopontin, Golgi protein 73, human β - defensin-1, etc.these biomarkers are of great significance for early identification of patients with liver failure, accurate evaluation of their prognosis, and formulation of effective treatment plan. Key words: Liver failure; Prognosis; Neutrophil/lymphocyte ratio; Golgi protein 73; Human β-defensin-1

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来源期刊

中国综合临床

CiteScore

0.10

自引率

0.00%

发文量

16855

期刊介绍： Clinical Medicine of China is an academic journal organized by the Chinese Medical Association (CMA), which mainly publishes original research papers, reviews and commentaries in the field. Clinical Medicine of China is a source journal of Peking University (2000 and 2004 editions), a core journal of Chinese science and technology, an academic journal of RCCSE China Core (Extended Edition), and has been published in Chemical Abstracts of the United States (CA), Abstracts Journal of Russia (AJ), Chinese Core Journals (Selection) Database, Chinese Science and Technology Materials Directory, Wanfang Database, China Academic Journal Database, JST Japan Science and Technology Agency Database (Japanese) (2018) and other databases.