{"title":"如何根据特异性IgM和IgG抗体的血清学检测获得冠状病毒垂直传播的证据","authors":"Chen Wang, Yihua Zhou, Huixia Yang","doi":"10.3760/CMA.J.CN113903-20200402-00301","DOIUrl":null,"url":null,"abstract":"Whether 2019 novel coronavirus can be vertically transmitted to fetuses is a major concern, while how to obtain evidence of vertical transmission in viral infected pregnant women is the key. Virological and serological evidence is valuable to clarify this issue. However, longitudinal follow-up of infants for at least 3-6 months after birth and dynamic changes of specific antibodies of the mothers is essential when serological results are used to confirm or exclude vertical transmission. \n \nKey words: \nCoronavirus infections; Infectious disease transmission, vertical; Immunoglobulin M; Immunoglobulin G","PeriodicalId":52320,"journal":{"name":"中华围产医学杂志","volume":"23 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"How to obtain evidence of vertical transmission of coronavirus according to serological test of specific IgM and IgG antibodies\",\"authors\":\"Chen Wang, Yihua Zhou, Huixia Yang\",\"doi\":\"10.3760/CMA.J.CN113903-20200402-00301\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Whether 2019 novel coronavirus can be vertically transmitted to fetuses is a major concern, while how to obtain evidence of vertical transmission in viral infected pregnant women is the key. Virological and serological evidence is valuable to clarify this issue. However, longitudinal follow-up of infants for at least 3-6 months after birth and dynamic changes of specific antibodies of the mothers is essential when serological results are used to confirm or exclude vertical transmission. \\n \\nKey words: \\nCoronavirus infections; Infectious disease transmission, vertical; Immunoglobulin M; Immunoglobulin G\",\"PeriodicalId\":52320,\"journal\":{\"name\":\"中华围产医学杂志\",\"volume\":\"23 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-04-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"中华围产医学杂志\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3760/CMA.J.CN113903-20200402-00301\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"中华围产医学杂志","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/CMA.J.CN113903-20200402-00301","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
How to obtain evidence of vertical transmission of coronavirus according to serological test of specific IgM and IgG antibodies
Whether 2019 novel coronavirus can be vertically transmitted to fetuses is a major concern, while how to obtain evidence of vertical transmission in viral infected pregnant women is the key. Virological and serological evidence is valuable to clarify this issue. However, longitudinal follow-up of infants for at least 3-6 months after birth and dynamic changes of specific antibodies of the mothers is essential when serological results are used to confirm or exclude vertical transmission.
Key words:
Coronavirus infections; Infectious disease transmission, vertical; Immunoglobulin M; Immunoglobulin G
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