氧化还原修饰和血液肿瘤综述

F. C. Campos
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引用次数: 1

摘要

由于我们目前对血液系统恶性肿瘤与氧化应激之间的关系的研究感兴趣,在这篇综述中,我们讨论了关于这一问题的最新发现,重点是关于血液系统癌症诊断患者氧化状态的临床发现。本研究是对文献的描述性综述。对于理论科学背景,我们使用了PubMed电子搜索引擎。有可能找到一些涉及氧化应激和血液学癌症的研究,分析了过多自由基产生的不平衡及其被抗氧化剂中和的许多途径。本综述强调需要研究了解氧化应激作为血液学肿瘤的原因或后果的主要作用,以及它对宿主或肿瘤细胞的有益参与。
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Redox Modifications and Hematological Neoplasms-an Overview
Due to our current interest in the study of the relationship between hematological malignancies and oxidative stress, in this review we addressed the recent finding regarding this issue, focusing on the clinical findings concerning the oxidative status of patients diagnosed with hematological cancers. This study is a descriptive review of the literature. For the theoretical scientific background, we used the electronic PubMed search engines. It is possible to find several studies involving oxidative stress and hematological cancer, analyzing the many ways regarding the imbalance of excessive free radical production and its neutralization by antioxidants. The present review highlights the need for studies to understand the main role of oxidative stress as a cause or consequence of hematological neoplasms, as well as its participation as beneficial for either the host or tumor cells.
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