{"title":"打开黑盒子:中国仓鼠卵巢研究走向基因组尺度","authors":"N. Borth","doi":"10.4155/PBP.14.42","DOIUrl":null,"url":null,"abstract":"The scientific community of Chinese hamster ovary (CHO)-cell scientists had a meeting to discuss the opportunities and requirements for a new era of genome scale science for CHO cells. With multiple genome sequences available, the challenge to the field is to use approaches of systems and synthetic biology to enhance quality and yield of recombinant therapeutics from CHO.","PeriodicalId":90285,"journal":{"name":"Pharmaceutical bioprocessing","volume":"2 1","pages":"367-369"},"PeriodicalIF":0.0000,"publicationDate":"2014-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4155/PBP.14.42","citationCount":"9","resultStr":"{\"title\":\"Opening the black box: Chinese hamster ovary research goes genome scale\",\"authors\":\"N. Borth\",\"doi\":\"10.4155/PBP.14.42\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The scientific community of Chinese hamster ovary (CHO)-cell scientists had a meeting to discuss the opportunities and requirements for a new era of genome scale science for CHO cells. With multiple genome sequences available, the challenge to the field is to use approaches of systems and synthetic biology to enhance quality and yield of recombinant therapeutics from CHO.\",\"PeriodicalId\":90285,\"journal\":{\"name\":\"Pharmaceutical bioprocessing\",\"volume\":\"2 1\",\"pages\":\"367-369\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2014-11-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.4155/PBP.14.42\",\"citationCount\":\"9\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pharmaceutical bioprocessing\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4155/PBP.14.42\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pharmaceutical bioprocessing","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4155/PBP.14.42","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Opening the black box: Chinese hamster ovary research goes genome scale
The scientific community of Chinese hamster ovary (CHO)-cell scientists had a meeting to discuss the opportunities and requirements for a new era of genome scale science for CHO cells. With multiple genome sequences available, the challenge to the field is to use approaches of systems and synthetic biology to enhance quality and yield of recombinant therapeutics from CHO.