地震后对一般人群中戊型肝炎患病率的评估

S. Khadka, Subhash Dhital, Baniya Jb, B. Shrestha, S. Tiwari, S. Poudel, S. Subedi, K. Kc, L. Shrestha, S. Mishra, R. Br, Upadhayay Bp, M. Sharma, Mahto Rm, G. Shakya
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摘要

戊型肝炎病毒(HEV)感染是一种引起急性肝炎的全球性疾病,通过粪便污染的水传播。在东南亚国家,如尼泊尔,戊型肝炎病毒是散发的病毒性肝炎和疫情的最常见病原体。尼泊尔4月发生地震后,病毒性肝炎的风险有所上升。这项研究的目的是发现普通人群中HEV特异性IgM的患病率。使用万泰HEV-IgM ELISA对570名健康人群的血液样本进行HEV IgM检测,发现1.40%的研究人群携带HEV IgM。该研究促进了病毒与人类宿主的低水平接触。
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Post-Earth Quake assessment of HEV prevalence among general population
Hepatitis E virus (HEV) infection is a global disease causing acute hepatitis, transmitted by fecal contaminated water. In South East Asian countries like, Nepal Hepatitis E virus is a most common causative agent of sporadic viral hepatitis and outbreaks. The risk of viral hepatitis has escalated after April earth quake in Nepal. The study was done with the objective to find the prevalence of HEV specific IgM among the general population. Blood samples from 570 healthy populations were tested for HEV IgM by using the Wantai HEV-IgM ELISA, and 1.40% of the study population is found to be harboring the HEV IgM. The study fostered the low level exposure to virus with human reservoirs.
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