季节性变应性鼻炎患者的长期自然病程

Mehmet Erdem Çakmak, Saltuk Buğra Kaya, Özge Can Bostan, E. Damadoğlu, G. Karakaya, A. Fuat Kalyoncu
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摘要

简介:季节性变应性鼻炎(SAR)的典型特征是流涕、鼻塞、打喷嚏和鼻、眼、耳、咽瘙痒。目的:评价SAR患者的自然病程。材料和方法:本研究纳入2009年1月前诊断为SAR的191例患者,并对其进行随访。在2019年6月至2020年6月期间,对这191人进行了调查。患者被要求比较他们最初的症状和去年的症状。结果:本研究中191例患者的中位年龄为35岁(范围:22-70岁),中位SAR持续时间为15年(范围:10-40年)。伴发SAR的最常见疾病为哮喘(n = 93, 48.7%)。最常见致敏变应原为鼻黏膜(n = 180, 94.2%),最常见症状为鼻分泌物(n = 178, 93.2%)、鼻痒(n = 176, 92.1%)、打喷嚏(n = 182, 95.3%)、眼痒(n = 136, 71.2%)和眼分泌物(n = 129, 67.5%)。在过去一年中,49例(25.7%)患者鼻症状加重,78例(40.8%)患者症状减轻,64例(33.5%)患者症状无变化。眼部症状加重26例(18.7%),减轻65例(46.7%),无变化48例(34.5%)。采用花粉避免策略的患者鼻症状减轻(p = 0.008)。结论:SAR的自然病程在长期随访中是可变的。实施有效的花粉避免措施可以长期降低SAR患者的病情严重程度。
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Long-term natural course of patients with seasonal allergic rhinitis
Introduction: Seasonal allergic rhinitis (SAR) is typically characterized by rhinorrhea, nasal congestion, sneezing, and itching of the nose, eyes, ears, and pharynx. Aim: To evaluate the natural course of the disease in patients diagnosed with SAR. Material and methods: The study included 191 patients diagnosed with SAR before January 2009 and who were followed up in our clinic. A survey was applied to these 191 between June 2019 and June 2020. Patients were asked to compare their initial symptoms and symptoms in the last year. Results: The median age of the 191 patients in this study was 35 (range: 22–70 years) and median SAR duration was 15 (range: 10–40 years). The most common disease accompanying SAR was asthma ( n = 93, 48.7%). The most common sensitizing allergen was Phleum pratense ( n = 180, 94.2%) and the most common symptoms were nasal discharge ( n = 178, 93.2%), nasal itching ( n = 176, 92.1%), sneezing ( n = 182, 95.3%), ocular itching ( n = 136, 71.2%) and ocular discharge ( n = 129, 67.5%). Over the past year, nasal symptoms increased in 49 (25.7%) patients, decreased in 78 (40.8%) and did not change in 64 (33.5%). Ocular symptoms increased in 26 (18.7%) patients, decreased in 65 (46.7%) and did not change in 48 (34.5%). Nasal symptoms decreased in patients who applied pollen avoidance strategies ( p = 0.008). Conclusions: The natural course of SAR in long-term follow-up is variable. The implementation of effective pollen avoidance measures can reduce the disease severity in patients with SAR in the long term.
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来源期刊
自引率
50.00%
发文量
18
期刊介绍: Alergologia Polska - Polish Journal of Allergology is aimed mainly at allergologists, but also medical doctors working in related fields, such as otolaryngology, pulmonology, and dermatology. The main goal of the journal is to ensure rapid publication of important research papers and interesting case studies from the following areas: allergology, diagnostics, therapy of allergic diseases, in particular in the area of immunotherapy, rhinitis, asthma. The Editorial Board accepts for publication original papers, case studies and letters to the Editor. We also publish review articles (both commissioned and those agreed upon with the Editor-in-Chief), articles dealing with standards of medical practice, as well as special issues. The journal is published quarterly. We guarantee short review times (up to two weeks) and immediate publication on-line upon Editor acceptance.
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