{"title":"在COVID-19诊断和医疗建议的背景下假阳性(结果)的概念","authors":"E. Stoczyńska-Fidelus, P. Rieske","doi":"10.5114/pja.2022.116289","DOIUrl":null,"url":null,"abstract":"COVID-19 is an example of a big challenge for diagnostics. In the case of many diseases and syndromes, there is a possibility to repeat the tests, and the time allocated for diagnosis is counted even in weeks, not in hours, as in COVID-19. The situation related to COVID-19, therefore leads to a large number of tensions, both among diagnostic physicians and patients. Especially that in this case, based on a positive result, the decision is being made not only about the choice of a possible therapy, but also about quarantine. This article refers to the predictive value of tests used in the diagnosis of COVID-19 (mainly RT-PCR), focusing on the concept of a false positive result. The article demonstrates that this is a relative term, depending on the question posed, the purpose of the diagnosis (selection of therapy, quarantine decision, disease detection), or even the variant of the SARS-CoV-2 virus. Effective vaccination against COVID-19, the increasing percentage of convalescent patients, and the emergence of the SARS-CoV-2 omicron variant minimalize all these problems. However, shifting away from widely used screening tests, should not cause abandoning COVID-19 testing completely. Part of the population may still die from the disease and effective targeted therapy already exists. In order to personalize this therapy, a test such as RT-PCR must be used.","PeriodicalId":7469,"journal":{"name":"Alergologia Polska - Polish Journal of Allergology","volume":null,"pages":null},"PeriodicalIF":0.2000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The concept of a false-positive (result) in the context of COVID-19 diagnostics and medical recommendations\",\"authors\":\"E. Stoczyńska-Fidelus, P. Rieske\",\"doi\":\"10.5114/pja.2022.116289\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"COVID-19 is an example of a big challenge for diagnostics. In the case of many diseases and syndromes, there is a possibility to repeat the tests, and the time allocated for diagnosis is counted even in weeks, not in hours, as in COVID-19. The situation related to COVID-19, therefore leads to a large number of tensions, both among diagnostic physicians and patients. Especially that in this case, based on a positive result, the decision is being made not only about the choice of a possible therapy, but also about quarantine. This article refers to the predictive value of tests used in the diagnosis of COVID-19 (mainly RT-PCR), focusing on the concept of a false positive result. The article demonstrates that this is a relative term, depending on the question posed, the purpose of the diagnosis (selection of therapy, quarantine decision, disease detection), or even the variant of the SARS-CoV-2 virus. Effective vaccination against COVID-19, the increasing percentage of convalescent patients, and the emergence of the SARS-CoV-2 omicron variant minimalize all these problems. However, shifting away from widely used screening tests, should not cause abandoning COVID-19 testing completely. Part of the population may still die from the disease and effective targeted therapy already exists. In order to personalize this therapy, a test such as RT-PCR must be used.\",\"PeriodicalId\":7469,\"journal\":{\"name\":\"Alergologia Polska - Polish Journal of Allergology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.2000,\"publicationDate\":\"2022-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Alergologia Polska - Polish Journal of Allergology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5114/pja.2022.116289\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"ALLERGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Alergologia Polska - Polish Journal of Allergology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5114/pja.2022.116289","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ALLERGY","Score":null,"Total":0}
The concept of a false-positive (result) in the context of COVID-19 diagnostics and medical recommendations
COVID-19 is an example of a big challenge for diagnostics. In the case of many diseases and syndromes, there is a possibility to repeat the tests, and the time allocated for diagnosis is counted even in weeks, not in hours, as in COVID-19. The situation related to COVID-19, therefore leads to a large number of tensions, both among diagnostic physicians and patients. Especially that in this case, based on a positive result, the decision is being made not only about the choice of a possible therapy, but also about quarantine. This article refers to the predictive value of tests used in the diagnosis of COVID-19 (mainly RT-PCR), focusing on the concept of a false positive result. The article demonstrates that this is a relative term, depending on the question posed, the purpose of the diagnosis (selection of therapy, quarantine decision, disease detection), or even the variant of the SARS-CoV-2 virus. Effective vaccination against COVID-19, the increasing percentage of convalescent patients, and the emergence of the SARS-CoV-2 omicron variant minimalize all these problems. However, shifting away from widely used screening tests, should not cause abandoning COVID-19 testing completely. Part of the population may still die from the disease and effective targeted therapy already exists. In order to personalize this therapy, a test such as RT-PCR must be used.
期刊介绍:
Alergologia Polska - Polish Journal of Allergology is aimed mainly at allergologists, but also medical doctors working in related fields, such as otolaryngology, pulmonology, and dermatology. The main goal of the journal is to ensure rapid publication of important research papers and interesting case studies from the following areas: allergology, diagnostics, therapy of allergic diseases, in particular in the area of immunotherapy, rhinitis, asthma. The Editorial Board accepts for publication original papers, case studies and letters to the Editor. We also publish review articles (both commissioned and those agreed upon with the Editor-in-Chief), articles dealing with standards of medical practice, as well as special issues. The journal is published quarterly. We guarantee short review times (up to two weeks) and immediate publication on-line upon Editor acceptance.