膀胱内卡介苗治疗及副作用:病例报告及文献回顾

S. Vasudeva, A. Baffoe-Bonnie
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引用次数: 4

摘要

随着人口老龄化的加剧,1期膀胱癌的膀胱内卡介苗植入越来越普遍。卡介苗可被全身吸收,并可在身体几乎任何器官形成肉芽肿,从接种卡介苗后几小时到几年后出现症状。在某些情况下,治疗方法可以从密切观察到使用异烟肼和利福平加或不加类固醇3-9个月。总体预后非常好。有必要提高医生对有卡介苗植入史的患者的卡介苗相关疾病过程的认识,以便进行适当的培养和治疗。
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Intravesical BCG Therapy and Side Effects-Case Reports and a Review of Literature
BCG installation in bladder for stage 1 bladder carcinoma is becoming more common with increasingly aging population. BCG can be absorbed systemically and cause granuloma formation in almost any organ of the body with symptom onset from a few hours after installation of BCG to several years later. The treatment can vary from close observation in some cases, to use of isoniazid and rifampin with and without steroids for 3-9 months. The overall prognosis is very good. There is need for greater awareness among physicians for considering BCG related disease processes in patients with past history of BCG installation so appropriate cultures can be send and treatment instituted.
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