微计算机断层扫描对陶瓷股骨头的磨损评估有用吗?体积测量的初步评价

A. Parrilli, S. Falcioni, M. Fini, S. Affatato
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引用次数: 10

摘要

背景与髋关节部件相关的磨损是这些患者的主要临床问题,开发新的技术来更准确地测量这种磨损是很重要的。目前,重量法是临床前评估中评估质量测量的金标准。然而,这种方法不提供其他信息,如体积损失或表面偏差。本研究旨在开发和验证一种利用微计算机断层扫描(micro-CT)从体外实验中量化陶瓷体积损失的新技术。方法采用氧化铝(BIOLOX®forte)股骨头(Ø = 28 mm)。质量损失和体积损失分别采用重量法(使用小数点后四位数字微天平)和Skyscan 1176显微层析系统。结果重量组和实验组的标准误差和方差系数均证明了微ct分析技术的可靠性。综上所述,本研究结果表明,该新方案可被认为是磨损评估的重要工具,我们已经找到了一种可靠的计量方案,用于陶瓷股骨头假体的体积分析,表明微ct技术可以成为磨损评估的重要工具。
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Is Micro-Computed Tomography Useful for Wear Assessment of Ceramic Femoral Heads? A Preliminary Evaluation of Volume Measurements
Background Wear associated with hip components represents the main clinical problem in these patients, and it is important to develop new techniques for more accurate measurements of that wear. Currently, the gravimetric method is the gold standard for assessing mass measurements in preclinical evaluations. However, this method does not give other information such as volumetric loss or surface deviation. This work aimed to develop and validate a new technique to quantify ceramic volume loss from in vitro experiments using micro-computed tomography (micro-CT). Methods An alumina (BIOLOX® forte) femoral head (Ø = 28 mm) was used. Mass and volume loss were approached by gravimetric method (using a four decimal place digital microbalance) and by using Skyscan 1176 microtomographic system, respectively. Results Standard error and coefficient of variance of both gravimetric and experimental groups demonstrated the reliability of the micro-CT analysis technique. Conclusions In conclusion, the findings of the present study suggest that this new protocol could be considered an important tool for wear assessment and that we have found a reliable metrological protocol for volumetric analysis of ceramic femoral head prostheses, demonstrating that the micro-CT technique can be an important tool for wear assessment.
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来源期刊
Journal of Applied Biomaterials & Biomechanics
Journal of Applied Biomaterials & Biomechanics 生物-材料科学:生物材料
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